Division of Gastroenterology, Hepatology, and Endoscopy, Center for Pancreatic Disease, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
Division of Gastroenterology, Hepatology and Nutrition, Ohio State University, 410 W 10th Ave Fl 2, Columbus, OH, 43210, USA.
Dig Dis Sci. 2018 Nov;63(11):2874-2879. doi: 10.1007/s10620-018-5206-1. Epub 2018 Jul 23.
Chronic pancreatitis (CP) is a debilitating chronic illness. We sought to assess the most common reasons patients with CP visit the Emergency Department (ED), the disposition of ED visit [admission, discharge, death], and evaluate predictors of admission and discharge.
Within the Health Care Utilization Project Nationwide Emergency Department Sample (NEDS), we focused on patients, 18 years and older, presenting to the emergency department with CP (ICD-9 code 577.1) (2006-2009). Model was fitted to predict the likelihood of admission.
Overall, a weighted sample of 638,310 patients visits for CP were identified, of which 399,559 (62.6%) were admitted, 228,523 (35.8%) were discharged from the ED, 5572 (0.9%) discharged against medical advice, and 4656 (0.7%) had an unknown destination. Of those admitted, 4370 (0.7%) died during the hospital episode. The most associated diagnoses for ED visit were diabetes (28.8%), abdominal pain (25.4%), acute pancreatitis (22.5%), cardiac complication (11.1%), infection (10.1%), and dehydration (8.8%). Multivariable analyses revealed that older (OR = 1.02 P < 0.001), sicker patients (Charlson Comorbidity Index ≥ 3, OR = 2.28 P < 0.001), patients presenting with C. difficile colitis (OR = 23.85 P < 0.001), alcohol withdrawal (OR = 6.71 P < 0.001), and acute pancreatitis (OR = 6.46 P < 0.001) were associated with increased odds of hospitalization.
In this national database, our study demonstrates that diabetes, followed by abdominal pain, acute pancreatitis and cardiac complication, were the most common diagnoses associated with ED visits in patients with chronic pancreatitis. Most patients were admitted following the ED visit. Although C. Difficile colitis was a rare associated diagnosis with an ED visit, it was the strongest predictor of admission.
慢性胰腺炎(CP)是一种使人虚弱的慢性疾病。我们旨在评估 CP 患者就诊急诊的最常见原因、急诊就诊的处置(入院、出院、死亡),并评估入院和出院的预测因素。
在全国急诊部样本(NEDS)医疗保健利用项目中,我们将重点放在因 CP(ICD-9 代码 577.1)就诊的 18 岁及以上患者身上(2006-2009 年)。建立模型以预测入院的可能性。
总体而言,在 CP 患者的加权样本中,有 638,310 人就诊,其中 399,559 人(62.6%)入院,228,523 人(35.8%)从 ED 出院,5572 人(0.9%)出院时违反医嘱,4656 人(0.7%)去向不明。在入院患者中,4370 人(0.7%)在住院期间死亡。急诊就诊最相关的诊断是糖尿病(28.8%)、腹痛(25.4%)、急性胰腺炎(22.5%)、心脏并发症(11.1%)、感染(10.1%)和脱水(8.8%)。多变量分析显示,年龄较大(OR=1.02,P<0.001)、病情较重(Charlson 合并症指数≥3,OR=2.28,P<0.001)、患有艰难梭菌结肠炎(OR=23.85,P<0.001)、酒精戒断(OR=6.71,P<0.001)和急性胰腺炎(OR=6.46,P<0.001)的患者住院的可能性更高。
在这个国家数据库中,我们的研究表明,糖尿病,其次是腹痛、急性胰腺炎和心脏并发症,是 CP 患者急诊就诊最常见的诊断。大多数患者在 ED 就诊后入院。尽管艰难梭菌结肠炎是 ED 就诊的罕见相关诊断,但它是入院的最强预测因素。