Ibrahim M, Omran A, AbdAllah N B, Ibrahim M, El-Sharkawy S
Departments of Pediatrics and Neonatology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Department of Radiodiagnosis, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
J Neonatal Perinatal Med. 2018;11(3):281-287. doi: 10.3233/NPM-181796.
Transient tachypnea of the newborn (TTN) is one of the most common causes of neonatal respiratory distress (RD). However, distinguishing TTN from other causes of RD may be difficult during the first 12:24 h after birth. Lung ultrasonography (LUS) has been successfully utilized in the diagnosis and differential diagnosis of neonatal RD. This study aimed to investigate the diagnostic value of LUS for early diagnosis of TTN as well as differentiate it from other causes of neonatal RD in near and full term Egyptian neonates.
LUS was performed in 65 near and full term neonates presented with RD within the first 12:24 hours of admission in NICU of Suez Canal University, Ismailia, Egypt.
Among the 65 neonates included in the study, 73.8% were diagnosed to have TTN, 18.5% were diagnosed to have pneumonia, 4.6% had meconium aspiration syndrome (MAS) and 3.1% had respiratory distress syndrome (RDS). The Double lung point has 69.6% sensitivity, 100% specificity, 100% PPV and 39.1% NPV for detecting TTN. We have novel data showing a positive correlation between the degree of alveolar-interstitial syndrome (AIS) and the type of oxygen support offered to neonates diagnosed with TTN.
We found LUS to be a reliable and non-invasive tool for the early diagnosis of TTN and its differentiation from other causes of neonatal RD in near and full term Egyptian neonates.
新生儿暂时性呼吸急促(TTN)是新生儿呼吸窘迫(RD)最常见的原因之一。然而,在出生后的最初12至24小时内,将TTN与其他导致RD的原因区分开来可能很困难。肺部超声检查(LUS)已成功应用于新生儿RD的诊断和鉴别诊断。本研究旨在探讨LUS对埃及近足月和足月儿TTN早期诊断的价值,并将其与其他导致新生儿RD的原因区分开来。
对埃及伊斯梅利亚苏伊士运河大学新生儿重症监护病房(NICU)收治的65例近足月和足月儿在入院后的最初12至24小时内进行了LUS检查。
在纳入研究的65例新生儿中,73.8%被诊断为TTN,18.5%被诊断为肺炎,4.6%患有胎粪吸入综合征(MAS),3.1%患有呼吸窘迫综合征(RDS)。双肺点对检测TTN的敏感性为69.6%,特异性为100%,阳性预测值为100%,阴性预测值为39.1%。我们有新的数据表明,肺泡间质综合征(AIS)的程度与诊断为TTN的新生儿所接受的氧疗类型之间存在正相关。
我们发现LUS是一种可靠的非侵入性工具,可用于埃及近足月和足月儿TTN的早期诊断及其与其他新生儿RD原因的鉴别。