Department of Analytical Chemistry and Toxicology, Ha Noi University of Pharmacy, 11-13 Le Thanh Tong, Hoan Kiem, Ha Noi, Viet Nam.
National Institute of Food Control, 65 Pham Than Duat, Cau Giay, Ha Noi, Viet Nam.
Mar Pollut Bull. 2018 Aug;133:911-919. doi: 10.1016/j.marpolbul.2018.06.045. Epub 2018 Jun 29.
The occurrence of okadaic acid (OA) group toxins in bivalve mollusk collected from Vietnamese coastal areas was investigated from April 2016 to April 2017. OA group toxins were detected in mollusk by UPLC-MS/MS with the highest level of 11.3 ng/g and detection frequency of 11.8%. Toxins were detected more frequently in dry season (14.4% of analyzed samples) than in wet season (7.9%). Toxins were also detected more frequently at sampling locations in the northern parts (≥10.4%) than in the southern part (≤8.3%) of Vietnamese coastline. Results of this study were similar to those obtained in long-term studies in regions geographically close to Vietnam, confirming decisive influence of geographic location on the accumulation of toxins in mollusks. Within the scope of the study, toxin levels in all contaminated samples were below the regulation limit (160 ng/g), but the presence of OA group toxins in bivalve mollusk suggests the need of a more stringent control of toxins in bivalve mollusk in Vietnam.
本研究于 2016 年 4 月至 2017 年 4 月期间调查了越南沿海地区贝类中麻痹性贝类毒素（OA 组）的发生情况。采用 UPLC-MS/MS 法检测贝类中的 OA 组毒素，最高含量为 11.3ng/g，检出率为 11.8%。毒素在旱季（14.4%的分析样本）的检出频率高于雨季（7.9%）。在越南北部（≥10.4%）的采样点也比南部（≤8.3%）更频繁地检测到毒素。本研究结果与越南地理位置相近地区的长期研究结果相似，证实了地理位置对贝类毒素积累的决定性影响。在所研究的范围内，所有受污染样品中的毒素含量均低于规定限量（160ng/g），但贝类中存在 OA 组毒素表明有必要在越南对贝类中的毒素进行更严格的控制。
