Pilgrim J P, Kloss S G, Wolfish P S, Heng M C
Am J Dermatopathol. 1985 Oct;7(5):461-9. doi: 10.1097/00000372-198510000-00011.
Primary mucinous carcinoma is a rare sweat-gland neoplasm of the skin with a tendency to grow slowly. Although the neoplasm persists locally in nearly half of the cases after attempts at removal, metastases to regional lymph nodes and widespread metastases are uncommon. We present a case of primary mucinous carcinoma in an axilla with metastases to the axillary lymph nodes and propose a hypothesis explaining the slow rate of growth, based on our findings of a paucity of both blood vessels and macrophages in the neoplasm. Electron microscopy revealed mucin production by the dark cell and its extracellular secretion, which supports the theory of eccrine differentiation of the neoplasm.
原发性黏液癌是一种罕见的皮肤汗腺肿瘤，生长缓慢。尽管在切除后近一半的病例中肿瘤仍会局部残留，但区域淋巴结转移和广泛转移并不常见。我们报告一例腋窝原发性黏液癌伴有腋窝淋巴结转移的病例，并根据我们在肿瘤中发现的血管和巨噬细胞数量稀少的情况，提出一个解释其生长缓慢的假说。电子显微镜显示暗细胞产生黏液并分泌到细胞外，这支持了该肿瘤汗腺分化的理论。
