Dang Audrey, Kupelian Patrick A, Cao Minsong, Agazaryan Nzhde, Kishan Amar U
Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Transl Androl Urol. 2018 Jun;7(3):308-320. doi: 10.21037/tau.2017.12.37.
Intensity-modulated radiotherapy (IMRT) has become the standard radiotherapy technology utilized for the treatment of prostate cancer, as it permits the delivery of highly conformal radiation dose distributions. Image-guided radiotherapy (IGRT) is an essential companion to IMRT that allows the treatment team to account for daily changes in target anatomy and positioning. In the present review, we will discuss the different sources of geometric uncertainty and review the rationale behind using IGRT in the treatment of prostate cancer. We will then describe commonly employed IGRT techniques and review their benefits and drawbacks. Additionally, we will review the evidence suggesting a potential clinical benefit to utilizing IGRT.
调强放射治疗（IMRT）已成为用于治疗前列腺癌的标准放射治疗技术，因为它能够实现高度适形的放射剂量分布。图像引导放射治疗（IGRT）是IMRT的重要辅助手段，它使治疗团队能够考虑靶区解剖结构和定位的每日变化。在本综述中，我们将讨论几何不确定性的不同来源，并回顾在前列腺癌治疗中使用IGRT的基本原理。然后，我们将描述常用的IGRT技术，并回顾它们的优缺点。此外，我们将综述表明使用IGRT具有潜在临床益处的证据。
