Saadat Payam, Ahmadi Ahangar Alijan, Babaei Mansor, Kalantar Mandana, Bayani Mohammad Ali, Barzegar Hiva, Gholinia Hemmat, Zahedi Tajrishi Farbod, Faraji Sekineh, Frajzadeh Fatemeh
Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Department of Internal Medicine, School of Medicine, Babol University of Medical Sciences, Babol, Iran.
Stroke Res Treat. 2018 Jul 2;2018:6580178. doi: 10.1155/2018/6580178. eCollection 2018.
Stroke is one of the most common neurological disorders with high mortality rates. A large financial burden is imposed on the families and health systems of countries in addition to the problems related to the disabilities caused by the disease for the patients. Extensive research is being conducted on the disease, including studies seeking possible relationships between some biomarkers such as uric acid and stroke.
This descriptive-analytic cross-sectional study was conducted on 170 stroke patients at Babol Ayatollah Rohani Hospital during 2015-2016. Serum uric acid (SUA) levels were measured and recorded at admission time. Patients' demographic data as well as the stroke type and some of their risk factors were entered in a checklist. The data were analyzed by SPSS.v.23 using chi-square and logistic regression tests. < 0.05 was considered as significant in all analyses.
Of the total 170 included patients, 57% had normal, 25% had low, and the remaining patients (18%) had high SUA levels. There was no significant difference in SUA levels in different types of stroke in both genders. Diabetic ischemic embolic patients had higher levels of SUA than diabetic ischemic thrombotic cases. Patients with low magnesium levels had higher rate of low levels of SUA in ischemic stroke.
Serum uric acid levels are not associated with stroke types and gender. Diabetic embolic ischemic stroke cases had high SUA levels than thrombotic types and in ischemic stroke patients with low serum levels of magnesium, SUA levels were also lower.
中风是最常见的神经系统疾病之一，死亡率很高。除了给患者带来与疾病所致残疾相关的问题外，还给家庭和国家卫生系统带来了巨大的经济负担。目前正在对该疾病进行广泛研究，包括寻找尿酸等一些生物标志物与中风之间可能存在的关系的研究。
本描述性分析横断面研究于2015 - 2016年在巴博勒阿亚图拉·罗哈尼医院对170例中风患者进行。在入院时测量并记录血清尿酸（SUA）水平。将患者的人口统计学数据以及中风类型和一些危险因素录入检查表。使用SPSS.v.23通过卡方检验和逻辑回归检验对数据进行分析。在所有分析中，P < 0.05被视为具有统计学意义。
在纳入的170例患者中，57%的患者SUA水平正常，25%的患者SUA水平低，其余患者（18%）SUA水平高。不同类型中风的SUA水平在男女之间均无显著差异。糖尿病缺血性栓塞患者的SUA水平高于糖尿病缺血性血栓形成患者。低镁水平的缺血性中风患者SUA低水平发生率更高。
血清尿酸水平与中风类型和性别无关。糖尿病栓塞性缺血性中风患者的SUA水平高于血栓形成类型患者，且血清镁水平低的缺血性中风患者的SUA水平也较低。
