• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

高危患者侵袭性真菌感染:2017年TIMM-8报告

Invasive fungal infections in high-risk patients: report from TIMM-8 2017.

作者信息

Pagano Livio, Mayor Susan

机构信息

Institute of Hematology, Fondazione Policlinico Universitario A. Gemelli- Università Cattolica del Sacro Cuore, Rome, Italy.

Medical writer, London, UK.

出版信息

Future Sci OA. 2018 Jun 14;4(6):FSO307. doi: 10.4155/fsoa-2018-0019. eCollection 2018 Jul.

DOI:10.4155/fsoa-2018-0019
PMID:30057784
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6060393/
Abstract

Trends in Medical Mycology (TIMM) is the biennial meeting of the Infectious Disease Group of the European Organisation for Research and Treatment of Cancer (EORTC) and the European Confederation of Medical Mycology (ECMM). It brings together clinicians and researchers from across the world to share the latest R&Ds in medical mycology. Despite advances in treatment, invasive fungal infections remain a major cause of morbidity and mortality in certain high-risk groups of patients, particularly in immunocompromised patients, including those undergoing solid organ transplantation and those with acute leukemia. The challenges for clinicians are now compounded by the rapid development of multidrug resistance. The latest data and approaches to identifying patients at high risk for invasive fungal infections, ensuring early diagnosis and achieving effective treatment, including when and how to use therapeutic drug monitoring with azoles, were shared with >1000 clinicians and researchers from around the world attending the eighth TIMM, held in Belgrade, Serbia, in October 2017 (TIMM-8 2017).

摘要

《医学真菌学趋势》(TIMM)是欧洲癌症研究与治疗组织(EORTC)传染病小组和欧洲医学真菌学联合会(ECMM)的两年一次会议。它汇聚了来自世界各地的临床医生和研究人员,以分享医学真菌学的最新研发成果。尽管在治疗方面取得了进展,但侵袭性真菌感染仍然是某些高危患者群体发病和死亡的主要原因,特别是在免疫功能低下的患者中,包括接受实体器官移植的患者和急性白血病患者。多药耐药性的迅速发展使临床医生面临的挑战更加复杂。2017年10月在塞尔维亚贝尔格莱德举行的第八届TIMM(TIMM - 8 2017)上,与来自世界各地的1000多名临床医生和研究人员分享了关于识别侵袭性真菌感染高危患者、确保早期诊断以及实现有效治疗的最新数据和方法,包括何时以及如何使用唑类药物的治疗药物监测。

相似文献

1
Invasive fungal infections in high-risk patients: report from TIMM-8 2017.高危患者侵袭性真菌感染:2017年TIMM-8报告
Future Sci OA. 2018 Jun 14;4(6):FSO307. doi: 10.4155/fsoa-2018-0019. eCollection 2018 Jul.
2
Improving outcome of fungal diseases - Guiding experts and patients towards excellence.改善真菌病治疗效果——引导专家和患者走向卓越。
Mycoses. 2017 Jul;60(7):420-425. doi: 10.1111/myc.12628. Epub 2017 May 12.
3
European confederation of medical mycology expert consult-An ECMM excellence center initiative.欧洲医学真菌学联合会专家咨询-ECMM 卓越中心倡议。
Mycoses. 2020 Jun;63(6):566-572. doi: 10.1111/myc.13076. Epub 2020 Apr 13.
4
Global guidelines and initiatives from the European Confederation of Medical Mycology to improve patient care and research worldwide: New leadership is about working together.欧洲医学真菌联合会改善全球患者护理和研究的全球指南和倡议:新领导层是要共同努力。
Mycoses. 2018 Nov;61(11):885-894. doi: 10.1111/myc.12836. Epub 2018 Aug 28.
5
Diagnosis of Breakthrough Fungal Infections in the Clinical Mycology Laboratory: An ECMM Consensus Statement.临床真菌学实验室中突破性真菌感染的诊断:欧洲医学真菌学联盟共识声明
J Fungi (Basel). 2020 Oct 11;6(4):216. doi: 10.3390/jof6040216.
6
8th Trends in Medical Mycology, Organised under the auspices of EORTC-IDG and ECMM, 6-9 October 2017, Belgrade, Serbia.第八届医学真菌学趋势研讨会,由欧洲癌症研究与治疗组织-侵袭性真菌感染协作组(EORTC-IDG)和欧洲临床微生物与感染性疾病学会(ECMM)主办,2017年10月6日至9日于塞尔维亚贝尔格莱德召开。
Mycoses. 2017 Sep;60 Suppl 2:3-238. doi: 10.1111/myc.12667.
7
9th Trends in Medical Mycology Held on 11-14 October 2019, Nice, France, Organized under the Auspices of EORTC-IDG and ECMM.第九届医学真菌学趋势会议于2019年10月11日至14日在法国尼斯举行,由欧洲癌症研究与治疗组织-侵袭性真菌感染研究组(EORTC-IDG)和欧洲医学真菌学联盟(ECMM)主办。
J Fungi (Basel). 2019 Oct 8;5(4):95. doi: 10.3390/jof5040095.
8
Clinicians' challenges in managing patients with invasive fungal diseases in seven Asian countries: An Asia Fungal Working Group (AFWG) Survey.亚洲七个国家临床医生管理侵袭性真菌感染患者的挑战:亚洲真菌感染工作组(AFWG)调查。
Int J Infect Dis. 2020 Jun;95:471-480. doi: 10.1016/j.ijid.2020.01.007. Epub 2020 Jan 13.
9
Developing collaborative works for faster progress on fungal respiratory infections in cystic fibrosis.开展合作项目以更快推进囊性纤维化患者真菌性呼吸道感染的研究进展。
Med Mycol. 2018 Apr 1;56(suppl_1):42-59. doi: 10.1093/mmy/myx106.
10
Emerging fungal infections.新发真菌感染。
Expert Rev Anti Infect Ther. 2012 Apr;10(4):419-21. doi: 10.1586/eri.12.14.

引用本文的文献

1
Antifungal Activity of Electrochemically Etched Nanotextured Stainless Steel against Candida albicans and Fusarium oxysporum Fungal Cells.电化学蚀刻纳米纹理不锈钢对白色念珠菌和尖孢镰刀菌真菌细胞的抗真菌活性
ACS Omega. 2025 May 7;10(19):19326-19334. doi: 10.1021/acsomega.4c09511. eCollection 2025 May 20.
2
Identification and validation of diagnostic cut-offs of the ELISpot assay for the diagnosis of invasive aspergillosis in high-risk patients.鉴定和验证 ELISpot assay 对高危患者侵袭性曲霉菌病的诊断界值。
PLoS One. 2024 Jul 9;19(7):e0306728. doi: 10.1371/journal.pone.0306728. eCollection 2024.
3
INVASIVE FUNGAL INFECTIONS IN CHILDREN TREATED FOR HEMATOLOGIC MALIGNANCIES - A FIVE-YEAR SINGLE CENTER EXPERIENCE.血液系统恶性肿瘤患儿侵袭性真菌感染-五年单中心经验。
Acta Clin Croat. 2022 Dec;61(4):647-654. doi: 10.20471/acc.2022.61.04.11.
4
Diagnosis of invasive fungal infections: challenges and recent developments.侵袭性真菌感染的诊断:挑战与新进展。
J Biomed Sci. 2023 Jun 19;30(1):42. doi: 10.1186/s12929-023-00926-2.
5
Immunogenicity and protective efficacy of a pan-fungal vaccine in preclinical models of aspergillosis, candidiasis, and pneumocystosis.一种泛真菌疫苗在曲霉病、念珠菌病和肺孢子菌病临床前模型中的免疫原性和保护效力。
PNAS Nexus. 2022 Nov 4;1(5):pgac248. doi: 10.1093/pnasnexus/pgac248. eCollection 2022 Nov.
6
Invasive and Subcutaneous Infections Caused by Filamentous Fungi: Report from a Portuguese Multicentric Surveillance Program.丝状真菌引起的侵袭性和皮下感染:来自葡萄牙多中心监测项目的报告。
Microorganisms. 2022 May 11;10(5):1010. doi: 10.3390/microorganisms10051010.
7
Incidence of Invasive Fungal Infections in Patients Initiating Ibrutinib and Other Small Molecule Kinase Inhibitors-United States, July 2016-June 2019.2016 年 7 月至 2019 年 6 月期间开始使用伊布替尼和其他小分子激酶抑制剂的患者侵袭性真菌感染的发生率-美国。
Clin Infect Dis. 2022 Aug 25;75(2):334-337. doi: 10.1093/cid/ciab1026.
8
Ceragenin-Coated Non-Spherical Gold Nanoparticles as Novel Candidacidal Agents.角鲨素包被的非球形金纳米颗粒作为新型杀念珠菌剂
Pharmaceutics. 2021 Nov 16;13(11):1940. doi: 10.3390/pharmaceutics13111940.
9
Synthesis, Characterization, and Antifungal Activity of Silver Nanoparticles Embedded in Pullulan Matrices.普鲁兰多糖基质包埋的银纳米颗粒的合成、表征及抗真菌活性
Materials (Basel). 2021 Nov 20;14(22):7041. doi: 10.3390/ma14227041.
10
Global Prevalence of COVID-19-Associated Mucormycosis (CAM): Living Systematic Review and Meta-Analysis.新型冠状病毒肺炎相关毛霉菌病(CAM)的全球患病率:实时系统评价与荟萃分析
J Fungi (Basel). 2021 Nov 18;7(11):985. doi: 10.3390/jof7110985.

本文引用的文献

1
Call for Action: Invasive Fungal Infections Associated With Ibrutinib and Other Small Molecule Kinase Inhibitors Targeting Immune Signaling Pathways.行动呼吁:伊布替尼和其他靶向免疫信号通路的小分子激酶抑制剂相关的侵袭性真菌感染。
Clin Infect Dis. 2018 Jan 6;66(1):140-148. doi: 10.1093/cid/cix687.
2
Pharmacokinetics and safety results from the Phase 3 randomized, open-label, study of intravenous posaconazole in patients at risk of invasive fungal disease.来自一项 3 期随机、开放性、研究的药代动力学和安全性结果,研究了静脉用泊沙康唑在有侵袭性真菌感染风险的患者中的应用。
J Antimicrob Chemother. 2017 Dec 1;72(12):3406-3413. doi: 10.1093/jac/dkx263.
3
Safety study and therapeutic drug monitoring of the oral tablet formulation of posaconazole in patients with haematological malignancies.泊沙康唑口服片剂制剂在血液系统恶性肿瘤患者中的安全性研究及治疗药物监测。
J Cancer Res Clin Oncol. 2018 Jan;144(1):127-134. doi: 10.1007/s00432-017-2523-2. Epub 2017 Sep 20.
4
Cytomegalovirus Reactivation Is Associated with Increased Risk of Late-Onset Invasive Fungal Disease after Allogeneic Hematopoietic Stem Cell Transplantation: A Multicenter Study in the Current Era of Viral Load Monitoring.巨细胞病毒再激活与异基因造血干细胞移植后晚期侵袭性真菌感染风险增加相关:病毒载量监测时代的多中心研究。
Biol Blood Marrow Transplant. 2017 Nov;23(11):1961-1967. doi: 10.1016/j.bbmt.2017.07.025. Epub 2017 Aug 7.
5
Candida and invasive mould diseases in non-neutropenic critically ill patients and patients with haematological cancer.非中性粒细胞减少危重症患者和血液恶性肿瘤患者的念珠菌和侵袭性霉菌病。
Lancet Infect Dis. 2017 Nov;17(11):e344-e356. doi: 10.1016/S1473-3099(17)30304-3. Epub 2017 Jul 31.
6
Evaluation of Posaconazole Serum Concentrations from Delayed-Release Tablets in Patients at High Risk for Fungal Infections.评估延迟释放片剂中泊沙康唑血清浓度在真菌感染高危患者中的应用。
Antimicrob Agents Chemother. 2017 Sep 22;61(10). doi: 10.1128/AAC.00569-17. Print 2017 Oct.
7
Changes in the incidence of candidemia and related mortality in patients with hematologic malignancies in the last ten years. A SEIFEM 2015-B report.过去十年血液系统恶性肿瘤患者念珠菌血症发病率及相关死亡率的变化。SEIFEM 2015 - B报告。
Haematologica. 2017 Oct;102(10):e407-e410. doi: 10.3324/haematol.2017.172536. Epub 2017 Jul 20.
8
Randomized comparison of liposomal amphotericin B versus placebo to prevent invasive mycoses in acute lymphoblastic leukaemia.脂质体两性霉素B与安慰剂预防急性淋巴细胞白血病侵袭性真菌病的随机对照研究
J Antimicrob Chemother. 2017 Aug 1;72(8):2359-2367. doi: 10.1093/jac/dkx133.
9
Multicentre study of posaconazole delayed-release tablet serum level and association with hepatotoxicity and QTc prolongation.泊沙康唑缓释片血清水平及其与肝毒性和QTc延长相关性的多中心研究。
J Antimicrob Chemother. 2017 Aug 1;72(8):2355-2358. doi: 10.1093/jac/dkx122.
10
Invasive mould infections in the ICU setting: complexities and solutions.重症监护病房环境中的侵袭性霉菌感染:复杂性与解决方案
J Antimicrob Chemother. 2017 Mar 1;72(suppl_1):i39-i47. doi: 10.1093/jac/dkx032.