Belachew Teshome, Mihret Amete, Legesse Tesfaye, Million Yihenew, Desta Kassu
Department of Medical Microbiology, School of Laboratory Medicine, College of Medicine and Health Sciences, University of Gondar, 196, Gondar, Ethiopia.
Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
BMC Res Notes. 2018 Jul 31;11(1):524. doi: 10.1186/s13104-018-3622-0.
The aim of this study was to determine the level of drug resistance by gram-negative bacteria isolated from selected sewage polluted urban rivers in Addis Ababa, Ethiopia.
From a total of 94 river water samples, 90 medically important gram-negative bacterial isolates were recovered to the species level. The predominant bacteria isolated were E. coli. 23 (26%) followed by K. pneumoniae 18 (20%), K. oxytoca 17 (19%). E. coli showed a high level of resistance to ampicillin 21 (91.3%), cefalotin, cefuroxime, ceftriaxone and cefepime 16 (70%). Both K. pneumoniae and K. oxytoca showed high resistance to ampicillin 16 (94%) and 17 (95%) respectively. Among identified bacterial species, most of them showed a multidrug-resistant pattern. Providential retigerri showed 100% multidrug resistance followed by P. alkalificiens (90%), E. coli (78%), M. morgani (75%), and C. frundi (60%).
本研究旨在确定从埃塞俄比亚亚的斯亚贝巴选定的受污水污染的城市河流中分离出的革兰氏阴性菌的耐药水平。
从总共94份河水样本中，共分离出90株具有医学重要性的革兰氏阴性菌，并鉴定到种水平。分离出的主要细菌为大肠杆菌，共23株（26%），其次是肺炎克雷伯菌18株（20%）、产酸克雷伯菌17株（19%）。大肠杆菌对氨苄西林耐药率较高，为21株（91.3%），对头孢噻吩、头孢呋辛、头孢曲松和头孢吡肟耐药率为16株（70%）。肺炎克雷伯菌和产酸克雷伯菌对氨苄西林的耐药率分别较高，为16株（94%）和17株（95%）。在鉴定出的细菌种类中，大多数呈现多重耐药模式。雷氏普罗威登斯菌的多重耐药率为100%，其次是产碱普罗威登斯菌（90%）、大肠杆菌（78%）、摩根摩根菌（75%）和弗氏柠檬酸杆菌（60%）。
