Pedraza M A
Cancer. 1977 Apr;39(4):1455-61. doi: 10.1002/1097-0142(197704)39:4<1455::aid-cncr2820390417>3.0.co;2-#.
A 69-year-old man with a mediastinal mass was found to have atypical lymphoid cells in peripheral blood and bone marrow. Light and electron microscopic studies showed that the mediastinal mass was a thymoma. B- and T-cell differentiation and PHA responsiveness in the tumor and peripheral blood were consistent with T-cells. After excision of the tumor and a course of radiotherapy the B/T ratio and PHA responsiveness in peripheral blood returned to normal while the atypical lymphocytes disappeared from circulation.