Patel Mayur Dilipbhai, Maitra Nandita, Patel Purvi K, Sheth Tosha, Vaishnav Palak
Department of Obstetrics and Gynecology, Medical College, Baroda, Vadodara, India.
J Obstet Gynaecol India. 2018 Aug;68(4):276-282. doi: 10.1007/s13224-017-1031-2. Epub 2017 Jul 7.
Attempting vaginal birth after cesarean section (VBAC) places women at an increased risk of complications. Trial of labor after cesarean (TOLAC) calculators aim to predict the chance of successful vaginal birth after cesarean (VBAC) based on the patient's preexisting demographic and clinical factors.
To assess the rate of successful TOLAC using two calculators: FLAMM and the Grobman calculator, and to compare the performance of the two calculators in the successful prediction of VBAC.
Prospective cohort study in subjects with previous one caesarean section using well-defined inclusion and exclusion criteria.
A total of 280 subjects with previous one cesarean section were enrolled. One hundred thirty-nine subjects consented for TOLAC, 90 (67%) underwent successful trial of vaginal birth, and 49 (32.8) required cesarean section. Cervical dilatation (p < 0.0001) and effacement (p < 0.0001), and any prior vaginal delivery (p < 0.02) were significantly associated with a successful outcome. At a cutoff score of 5, the sensitivity of the FLAMM score was 72% and specificity was 76%. For the Grobman calculator, the best sensitivity (69%) and specificity (67%) were seen at a cutoff score of 85%.
Both prediction models, the FLAMM and the "close to delivery" nomogram, recommended by Grobman et al. are easy to use and could successfully estimate the chances of vaginal birth in previous caesarean, in this small cohort. The decision for women opting for TOLAC can be individualized, and patient-specific chances of success can be predicted by the use of these prediction models.
剖宫产术后尝试经阴道分娩(VBAC)会使女性面临更高的并发症风险。剖宫产术后试产(TOLAC)计算器旨在根据患者先前的人口统计学和临床因素预测剖宫产术后经阴道成功分娩(VBAC)的几率。
使用两种计算器(FLAMM和Grobman计算器)评估TOLAC成功的发生率,并比较这两种计算器在成功预测VBAC方面的性能。
对有过一次剖宫产史的受试者进行前瞻性队列研究,采用明确的纳入和排除标准。
共纳入280例有过一次剖宫产史的受试者。139例受试者同意进行TOLAC,其中90例(67%)经阴道试产成功,49例(32.8%)需要剖宫产。宫颈扩张(p<0.0001)、宫颈消退(p<0.0001)以及既往任何经阴道分娩(p<0.02)与成功结局显著相关。在截断分数为5时,FLAMM评分的敏感性为72%,特异性为76%。对于Grobman计算器,在截断分数为85%时观察到最佳敏感性(69%)和特异性(67%)。
Grobman等人推荐的两种预测模型,即FLAMM和“接近分娩”列线图,易于使用,并且在这个小队列中能够成功估计既往剖宫产史患者经阴道分娩的几率。对于选择TOLAC的女性,决策可以个体化,使用这些预测模型可以预测患者个体的成功几率。