Tecnologica Research Institute, Biomedical Section, Crotone, Italy.
Eur Rev Med Pharmacol Sci. 2013 Jul;17(14):1958-62.
The healing of bone tissues around dental implants is based primarily on a correct osseointegration.
Typically, implants stability and peri-implant tissues health are anticipated to decrease during the early weeks of healing; this is followed by an increase in stability.
The aim of the present study is to assess a predictable protocol in order to increase the peri-implant tissues maintenance around post-extractive dental implants, thanks to the use of Platelet-Rich Fibrin (PRF) membrane.
This is a retrospective observational study of 127 tapered dental implants placed in the immediate post-extraction sites of maxillary bone of 59 patients. Atraumatic dental extraction and flapless implant surgery was performed in all reported cases. The cortical bone position relative to the implant reference point was evaluated at implant placement and 10 to 24 months following implantology. The gap between bone tissue and the implant surface was measured up to a maximum of 3 mm. After placing implants we have filled the surgical site with a PRF gel, so as to fill the gap between bone tissue and the implant surface, and then we have covered the surgical site with a PRF membrane, so as to coat the gap between the alveolar crest and the implant.
In all cases, we observed the complete covering of the dental implants, with newly formed soft tissue of variable thickness between 1 and 3 mm. Cortical bone adaptation from the time of implant placement up to 30 months following prosthetic restoration ranged from 0.4 mm to 1.7 mm.
Our study showed a series of successful rehabilitations, with post-extraction implantology technique, in 99.8 percent of cases, despite the success rates in the medium and long-term post-extraction implantology reported in the literature range between 92.7 percent and 98.0 percent. Long-term maintenance of crestal bone and the rapid healing of soft tissue dimension with maintenance of peri-implant papilla were observed as outcomes after post-extractive implants insertion.
骨组织在牙种植体周围的愈合主要基于正确的骨整合。
通常，在愈合的早期几周内，预计种植体的稳定性和种植体周围组织的健康状况会下降；随后稳定性会增加。
本研究旨在评估一种可预测的方案，以通过使用富含血小板纤维蛋白（PRF）膜来维持种植体周围组织的稳定性。
这是一项回顾性观察研究，共纳入 59 例患者的上颌骨即刻拔牙窝内植入的 127 个锥形种植体。所有病例均行无瓣微创拔牙和种植手术。在种植体植入时和植入后 10 至 24 个月评估皮质骨相对于种植体参考点的位置。测量骨组织与种植体表面之间的间隙，最大可达 3 毫米。植入种植体后，我们在手术部位填充 PRF 凝胶，以填充骨组织与种植体表面之间的间隙，然后用 PRF 膜覆盖手术部位，以覆盖牙槽嵴和种植体之间的间隙。
在所有病例中，我们观察到种植体完全覆盖，新形成的软组织厚度在 1 至 3 毫米之间。从种植体植入到修复后 30 个月，皮质骨的适应性范围从 0.4 毫米到 1.7 毫米。
尽管文献中报道的即刻拔牙后种植体的中远期成功率在 92.7%至 98.0%之间，但我们的研究显示，在 99.8%的病例中，通过即刻拔牙后种植体技术进行了一系列成功的修复。长期维持牙槽嵴骨和软组织快速愈合，保持种植体周围乳头。
