From the Sackler Program for Epigenetics and Psychobiology at McGill University, the Ludmer Centre for Neuroinformatics and Mental Health, and the Department of Psychiatry, McGill University, and the Douglas Mental Health University Research Centre, Montreal; and the Singapore Institute for Clinical Sciences, Singapore.
Am J Psychiatry. 2018 Nov 1;175(11):1084-1093. doi: 10.1176/appi.ajp.2018.17091031. Epub 2018 Aug 2.
The importance of maternal depression for child outcomes is well established, and impairments in psychosocial function and parenting are as severe in women with high subsyndromal levels of depressive symptoms as they are in women with clinical depression. The author conducted a systematic review that explored the association between maternal depressive symptoms and child neurodevelopmental outcomes, including in neuroimaging studies. The results strongly suggest that the influences of maternal depressive symptoms operate across a continuum to influence child outcomes, implying that maternal depression may appropriately be considered an issue of population health. This conclusion is strengthened by recent findings that reveal distinct influences of positive maternal mental health on parenting and child outcomes. [AJP AT 175: Remembering Our Past As We Envision Our Future April 1851: Fleetwood Churchill, "On the Mental Disorders of Pregnancy and Childbed" "Women affected with any degree of mental derangement during pregnancy are more disposed than others to puerperal mania. But the serious character of these attacks is even deepened by the fact, abundantly established, that the evil is not limited to the mother. Not only may organic diseases of the body be transmitted to the infant, but a predisposition to insanity, thus multiplying the distress in a most alarming ratio." (Am J Psychiatry 1851; 7:297-317 )].
母亲的抑郁对儿童结局的重要性已得到充分证实，高亚综合征水平的抑郁症状女性的心理社会功能和养育能力受损与临床抑郁症女性一样严重。作者进行了一项系统评价，探讨了母亲抑郁症状与儿童神经发育结局之间的关系，包括神经影像学研究。研究结果强烈表明，母亲抑郁症状的影响是连续的，会影响儿童的结局，这意味着母亲抑郁可能被恰当地视为人口健康问题。这一结论得到了最近的发现的支持，这些发现揭示了积极的母亲心理健康对养育和儿童结局的不同影响。[《美国精神病学杂志》175 卷：纪念过去，展望未来 1851 年 4 月：弗利特伍德·丘吉尔，“妊娠和产褥期精神障碍”“在妊娠期间患有任何程度精神错乱的女性比其他女性更容易患产后狂躁症。但这些攻击的严重程度甚至因以下事实而加深，即这种疾病不仅限于母亲。不仅身体的器质性疾病可能会传染给婴儿，而且还会导致精神错乱的倾向，从而以最惊人的比例增加痛苦。”（美国精神病学杂志 1851；7：297-317）]
