Dłużniewska Natalia, Podolec Piotr, Olszowska Maria, Weryński Piotr, Suder Bogdan, Kopeć Grzegorz, Tomkiewicz-Pająk Lidia
Department of Cardiac and Vascular Disease, Jagiellonian University Medical College, John Paul II Hospital, Krakow, Poland.
Clinic of Pediatric Cardiology, Polish-American Institute of Pediatrics, Jagiellonian University Medical College, Children's University Hospital, Krakow, Poland.
Kardiochir Torakochirurgia Pol. 2018 Jun;15(2):107-113. doi: 10.5114/kitp.2018.76476. Epub 2018 Jun 25.
Observations of patients after repair of tetralogy of Fallot (ToF) indicate good correction results and long-term survival. Few papers have been published in which the quality of life (QoL) of this population has been assessed.
AIM: To evaluate QoL in adults with repaired ToF. .
MATERIAL AND METHODS: We included 39 patients with repaired ToF and 40 age- and sex-matched healthy volunteers. Information recorded included echocardiography, cardiac magnetic resonance, cardiopulmonary exercise test, and self-reported health-related QoL questionnaire (SF-36). .
RESULTS: The perceived physical and mental domains of health were signi cantly poorer in ToF patients than in controls. A positive correlation between VO peak and physical domains was observed: (VO peak vs. physical domains ( = 0.6, ≤ 0.001), general health ( = 0.36, = 0.03), and physical complex status ( = 0.51, = 0.001). VO peak % correlated with physical functioning ( = 0.43, = 0.007), general health ( = 0.39, = 0.015) and physical complex status ( = 0.49, = 0.002). Right ventricle ejection fraction, determined with cardiac magnetic resonance, positively correlated with role physical ( = 0.38, = 0.04). In echocardiography, pressure half time was posi- tively correlated with physical functioning ( = 0.48, = 0.004) and role physical ( = 0.4, = 0.02). .
The QoL in adults after repair of ToF and healthy control subjects was compared directly. The self-perceived physical and mental domains of health were significantly poorer in ToF patients than in controls. Strong associations were found between objective exercise capacity and physical aspects of quality of life. Complex assessment and quality of life instruments should be used together to obtain an accurate view of health status of patients with repaired ToF.
对法洛四联症（ToF）修复术后患者的观察表明，矫正效果良好且长期生存率较高。很少有论文发表评估该人群的生活质量（QoL）。
评估法洛四联症修复术后成人的生活质量。
我们纳入了39例法洛四联症修复术后患者和40例年龄及性别匹配的健康志愿者。记录的信息包括超声心动图、心脏磁共振成像、心肺运动试验以及自我报告的与健康相关的生活质量问卷（SF - 36）。
法洛四联症患者在健康的身体和心理领域的自我认知明显比对照组差。观察到峰值摄氧量（VO₂peak）与身体领域之间存在正相关：（VO₂peak与身体领域（r = 0.6，p ≤ 0.001）、总体健康（r = 0.36，p = 0.03）以及身体综合状况（r = 0.51，p = 0.001））。VO₂peak%与身体功能（r = 0.43，p = 0.007）、总体健康（r = 0.39，p = 0.015）以及身体综合状况（r = 0.49，p = 0.002）相关。通过心脏磁共振成像测定的右心室射血分数与身体功能角色（r = 0.38，p = 0.04）呈正相关。在超声心动图中，压力减半时间与身体功能（r = 0.48，p = 0.004）和身体功能角色（r = 0.4，p = 0.02）呈正相关。
直接比较了法洛四联症修复术后成人与健康对照者的生活质量。法洛四联症患者在健康的身体和心理领域的自我认知明显比对照组差。发现客观运动能力与生活质量的身体方面之间存在密切关联。应同时使用综合评估和生活质量工具，以准确了解法洛四联症修复术后患者的健康状况。
