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精神障碍患者睡眠障碍症状的患病率及其相关因素。

Prevalence and correlates of sleep disorder symptoms in psychiatric disorders.

机构信息

Research Division, Institute of Mental Health, Buangkok Green Medical Park, 10 Buangkok View, 539747, Singapore.

Research Division, Institute of Mental Health, Buangkok Green Medical Park, 10 Buangkok View, 539747, Singapore.

出版信息

Psychiatry Res. 2019 Sep;279:116-122. doi: 10.1016/j.psychres.2018.07.009. Epub 2018 Jul 6.

Abstract

Difficulty falling asleep or maintaining sleep, poor sleep quality, nightmares, and excessive daytime sleepiness are some of the key clinical symptoms of sleep disturbances observed among individuals with psychiatric illnesses. This study aimed to determine the prevalence of symptoms of sleep disorders including parasomnia, narcolepsy, obstructive sleep apnea, circadian rhythm disorder and restless leg syndrome/periodic limb movement (RLS/PLMS) and its correlates in patients with psychiatric diagnoses. Patients aged 21-65 years (n = 400) attending the outpatient clinics with a primary diagnosis of either schizophrenia, mood or anxiety disorder based on ICD-9 criteria were included in this cross-sectional study. Sociodemographic information was collected and screening questions pertaining to specific symptoms of sleep disorders were administered by a study team member. The overall prevalence of symptoms of sleep disorders in the psychiatric outpatient sample was 40.75% (163/400). The prevalence for symptoms of narcolepsy, sleep breathing disorder, PLMS/RLS, circadian rhythm disorder and parasomnia were 12.5%, 14.5%, 14.8%, 4.5%, and 13.8% respectively. These symptoms were associated with age, low physical activity, and anxiety disorder. Results highlight the high prevalence of symptoms of sleep disorders in psychiatric patients. Present study findings should be confirmed using diagnostic interviews and objective measures.

摘要

入睡困难或维持睡眠困难、睡眠质量差、噩梦和白天过度嗜睡是精神疾病患者观察到的睡眠障碍的一些主要临床症状。本研究旨在确定精神疾病诊断患者的睡眠障碍症状(包括异态睡眠、发作性睡病、阻塞性睡眠呼吸暂停、昼夜节律障碍和不宁腿综合征/周期性肢体运动(RLS/PLMS)及其相关症状)的患病率。这项横断面研究纳入了年龄在 21-65 岁之间(n=400)、根据 ICD-9 标准诊断为精神分裂症、心境或焦虑障碍的门诊患者。收集了社会人口统计学信息,并由研究小组成员对特定睡眠障碍症状进行了筛查。在精神科门诊样本中,睡眠障碍症状的总体患病率为 40.75%(163/400)。发作性睡病、睡眠呼吸障碍、PLMS/RLS、昼夜节律障碍和异态睡眠的症状患病率分别为 12.5%、14.5%、14.8%、4.5%和 13.8%。这些症状与年龄、低体力活动和焦虑障碍有关。研究结果强调了精神疾病患者睡眠障碍症状的高患病率。本研究结果应使用诊断访谈和客观测量进行确认。

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