The Brain Tumor Institute, Center for Neuroscience and Behavioral Medicine, Children's National Health System, 111 Michigan Avenue Northwest, Washington, DC 20010, USA; Division of Oncology, Center for Cancer and Blood Disorders, 111 Michigan Avenue Northwest, Washington, DC 20010, USA.
The Brain Tumor Institute, Center for Neuroscience and Behavioral Medicine, Children's National Health System, 111 Michigan Avenue Northwest, Washington, DC 20010, USA; The Brain Tumor Institute, Gilbert Family Neurofibromatosis Institute, Children's National Medical Center, 111 Michigan Avenue Northwest, Washington, DC 20010, USA.
Neurol Clin. 2018 Aug;36(3):533-556. doi: 10.1016/j.ncl.2018.04.009.
Pediatric central nervous system (CNS) tumors are the most common solid tumors in children and comprise 15% to 20% of all malignancies in children. Presentation, symptoms, and signs depend on tumor location and age of the patient at the time of diagnosis. This article summarizes the common childhood CNS tumors, presentations, classification, and recent updates in treatment approaches due to the increased understanding of the molecular pathogenesis of pediatric brain tumors.
小儿中枢神经系统（CNS）肿瘤是儿童中最常见的实体瘤，占儿童所有恶性肿瘤的 15%至 20%。表现、症状和体征取决于肿瘤的位置和诊断时患者的年龄。本文总结了常见的小儿 CNS 肿瘤、表现、分类以及由于对小儿脑瘤分子发病机制的深入了解而在治疗方法上的最新进展。
