Anyang Eye Hospital, Henan Province, China.
Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Science Key Lab, Beijing Institute of Ophthalmology, Capital Medical University, Beijing, China.
Br J Ophthalmol. 2019 Jun;103(6):768-774. doi: 10.1136/bjophthalmol-2018-312114. Epub 2018 Aug 2.
To determine prevalence of refractive (RA), corneal (CA) and internal astigmatism (IA), including variation with gender and spherical equivalent refraction (SE), in a population of 12-year-old Chinese children.
A total of 1783 students with a mean age of 12.7 years (range 10.0-15.6 years) completed comprehensive eye examinations in the Anyang Childhood Eye Study. Data of cycloplegic refraction and corneal curvature were analysed.
Prevalences of RA, CA and IA ≥1.0 D were 17.4% (95%CI 15.6% to 19.2%), 52.8% (50.5% to 55.1%)%) and 20.9% (19.0% to 22.8%), respectively. With different limits of astigmatism axes classification, including ±15°, ±20° and ±30°, RA and CA axes were mainly 'with-the-rule' (WTR) (ie, correcting axis of negative cylinders at or near 180°), while those for IA axes were mainly 'against-the-rule' (ATR) (ie, correcting axis of negative cylinders at or near 90°). RA was not different between the genders, but girls had higher prevalence and greater means of CA and IA. RA and CA increased in students with higher ametropia (more myopia and more hyperopia) and were the highest in a high myopic group (SE≤-6 D), while IA was stable across refraction groups. Children with RA higher than 0.50 D were more likely to have lens corrections (51%, 57%, 61% and 69% for magnitudes of ≥0.50 D, ≥0.75 D, ≥1.0 D and ≥1.5 D, respectively).
Prevalence of RA in the Chinese 12-year-old children was relatively high compared with other studies. RA and CA had mainly 'WTR' astigmatism, while IA was mainly ATR and partially compensated for CA. Girls had greater means and prevalences of CA and IA than did boys. Both RA and CA, but not IA, increased with refractive errors away from emmetropia.
确定 12 岁中国儿童人群的屈光性(RA)、角膜性(CA)和内眼散光(IA)的患病率,包括性别和等效球镜(SE)的差异。
共有 1783 名平均年龄为 12.7 岁(范围 10.0-15.6 岁)的学生参加了安阳儿童眼研究的全面眼部检查。分析了睫状肌麻痹验光和角膜曲率的数据。
RA、CA 和 IA≥1.0D 的患病率分别为 17.4%(95%CI 15.6%19.2%)、52.8%(50.5%55.1%)和 20.9%(19.0%~22.8%)。在散光轴位分类的不同限值(包括±15°、±20°和±30°)下,RA 和 CA 轴位主要为顺规散光(即负柱镜矫正轴在或接近 180°),而 IA 轴位主要为逆规散光(即负柱镜矫正轴在或接近 90°)。RA 在性别间无差异,但女性的 CA 和 IA 患病率和平均值更高。RA 和 CA 在屈光不正程度较高的学生中增加(更多近视和更多远视),在高度近视组(SE≤-6D)中最高,而 IA 在各屈光组间稳定。RA 高于 0.50D 的儿童更有可能进行镜片矫正(RA 为 0.50D、0.75D、1.0D 和 1.5D 的儿童分别有 51%、57%、61%和 69%需要配镜)。
与其他研究相比,中国 12 岁儿童的 RA 患病率相对较高。RA 和 CA 主要为顺规散光,而 IA 主要为逆规散光,并部分补偿 CA。与男孩相比,女孩的 CA 和 IA 的平均值和患病率更高。RA 和 CA 均随屈光不正向远视或近视方向偏离而增加,但 IA 则不增加。