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代谢综合征对择期前路颈椎间盘切除融合术后 30 天结局的影响。

The Impact of Metabolic Syndrome on 30-Day Outcomes Following Elective Anterior Cervical Discectomy and Fusions.

机构信息

Department of Orthopaedics, The Ohio State University Wexner Medical Center, Columbus Ohio.

出版信息

Spine (Phila Pa 1976). 2019 Mar 1;44(5):E282-E287. doi: 10.1097/BRS.0000000000002824.

Abstract

STUDY DESIGN

Retrospective review of prospective registry OBJECTIVE.: To analyze the impact of metabolic syndrome (MetS) on 30-day outcomes following elective anterior cervical discectomy and fusions (ACDFs).

SUMMARY OF BACKGROUND DATA

MetS is defined as the presence of a combination of hypertension, diabetes mellitus, and obesity. Past literature has reported MetS to complicate postoperative care in patients undergoing various surgical procedures, including lumbar fusions.

METHODS

The 2015 to 2016 American College of Surgeons-National Surgical Quality Improvement Program (ACS-NSQIP) database was queried using current procedural terminology (CPT) codes 22,551 (single-level) and 22,552 (additional level). Patients undergoing disc arthroplasty, multi-level (>3) fusion, posterior cervical spine surgery, and patients with fracture, tumor, infection were excluded. MetS was defined using a pre-set criteria used by other NSQIP studies as the presence of-(1) diabetes mellitus, (2) hypertension requiring medication, and (3) body mass index (BMI) more than or equal to 30 kg/m.

RESULTS

A total of 1384 (8.8%) patients with MetS underwent a cervical fusion. Following adjusted analysis, results showed that presence of MetS was associated with higher odds of a prolonged length of stay more than or equal to 3 days (odds ratios [OR] 1.32 [95% confidence interval [CI] 1.12-1.56]; P = 0.001). No significant association was found between MetS and 30-day complications, 30-day reoperations, 30-day re-admissions, a non-home discharge, and death.

CONCLUSION

While MetS was associated with a prolonged length of stay, its presence does not have a large impact on 30-day outcomes following elective ACDF.

LEVEL OF EVIDENCE

摘要

研究设计

前瞻性注册回顾

目的

分析代谢综合征(MetS)对择期前路颈椎间盘切除融合术(ACDF)后 30 天结果的影响。

背景资料概要

MetS 定义为高血压、糖尿病和肥胖的组合存在。过去的文献报道,MetS 使接受各种手术的患者(包括腰椎融合术)的术后护理复杂化。

方法

使用当前程序术语 (CPT) 代码 22,551(单节段)和 22,552(附加节段),从 2015 年至 2016 年美国外科医师学会-国家外科质量改进计划 (ACS-NSQIP) 数据库中查询。排除接受椎间盘置换术、多节段 (>3) 融合术、后路颈椎手术以及骨折、肿瘤、感染患者。MetS 使用其他 NSQIP 研究中使用的预设标准定义为存在以下情况之一:(1) 糖尿病,(2) 需要药物治疗的高血压,和 (3) 体重指数 (BMI) 大于或等于 30kg/m。

结果

共有 1384 例 (8.8%) MetS 患者接受了颈椎融合术。经过调整分析,结果表明 MetS 的存在与 3 天以上的住院时间延长的可能性更高相关(优势比 [OR] 1.32 [95%置信区间 [CI] 1.12-1.56];P = 0.001)。MetS 与 30 天并发症、30 天再次手术、30 天再次入院、非家庭出院和死亡之间没有显著关联。

结论

虽然 MetS 与住院时间延长有关,但它的存在对择期 ACDF 后 30 天的结果影响不大。

证据水平

3 级。

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