与颈椎间盘置换术相比,单节段颈椎前路椎间盘切除融合术在肥胖患者中的非常规出院率更高。

Single-level anterior cervical discectomy and fusion is associated with higher nonroutine discharge rates compared to cervical disc arthroplasty in obese patients.

作者信息

Mastrokostas Paul G, Schwartz Luke B, Berglas Eli, Lavi Aaron B, Mastrokostas Leonidas E, Dalton Jonathan, Kepler Christopher K, Varthi Arya, Monsef Jad Bou, Razi Afshin E, Ng Mitchell K

机构信息

Department of Orthopaedic Surgery, SUNY Downstate Health Sciences University, Brooklyn, NY.

Department of Orthopaedic Surgery, Maimonides Medical Center, Brooklyn, NY.

出版信息

J Craniovertebr Junction Spine. 2025 Apr-Jun;16(2):205-211. doi: 10.4103/jcvjs.jcvjs_108_25. Epub 2025 Jul 3.

Abstract

CONTEXT

Obesity is a recognized risk factor for adverse outcomes in cervical spine surgery. While cervical disc arthroplasty (CDA) has emerged as an alternative to anterior cervical discectomy and fusion (ACDF), comparative outcomes among obese patients remain underexplored.

AIMS

The aim of this study is to compare nonroutine discharge rates and other postoperative outcomes between obese patients undergoing single-level ACDF and CDA.

SETTINGS AND DESIGN

Retrospective cohort study using a national database.

SUBJECTS AND METHODS

The National Inpatient Sample was queried to identify obese patients who underwent single-level ACDF or CDA between 2016 and 2020. Inclusion and exclusion criteria were applied. Propensity score matching (1:3) was performed based on age, sex, race, Elixhauser Comorbidity Index, and primary diagnosis to create comparable cohorts. Outcomes included nonroutine discharge, length of stay (LOS), total cost, and postoperative complications.

STATISTICAL ANALYSIS USED

Chi-square tests and Student's t-tests were used for categorical and continuous outcomes, respectively, with significance set at < 0.05.

RESULTS

After matching, 1455 ACDF and 485 CDA cases were analyzed. Obese patients undergoing ACDF had significantly higher nonroutine discharge rates (11.3% vs. 4.1%, = 0.037). ACDF patients had lower total costs ($16,400 vs. $19,400, = 0.003), with similar LOS (1.4 ± 0.1 days, = 0.931) and adverse event rates (7.6% vs. 8.2%, P = 0.827).

CONCLUSIONS

Obese patients undergoing ACDF experience higher nonroutine discharge rates compared to those receiving CDA. While CDA is associated with higher costs, it may offer superior discharge outcomes in this high-risk population.

摘要

背景

肥胖是颈椎手术不良预后的公认风险因素。虽然颈椎间盘置换术(CDA)已成为颈椎前路椎间盘切除融合术(ACDF)的替代方案,但肥胖患者的比较结果仍未得到充分研究。

目的

本研究的目的是比较接受单节段ACDF和CDA的肥胖患者的非常规出院率及其他术后结果。

设置与设计

使用国家数据库进行回顾性队列研究。

对象与方法

查询国家住院患者样本,以确定2016年至2020年间接受单节段ACDF或CDA的肥胖患者。应用纳入和排除标准。根据年龄、性别、种族、埃利克斯豪泽合并症指数和主要诊断进行倾向评分匹配(1:3),以创建可比队列。结果包括非常规出院、住院时间(LOS)、总费用和术后并发症。

所用统计分析方法

卡方检验和学生t检验分别用于分类结果和连续结果,显著性设定为<0.05。

结果

匹配后,分析了1455例ACDF和485例CDA病例。接受ACDF的肥胖患者非常规出院率显著更高(11.3%对4.1%,P = 0.037)。ACDF患者的总费用更低(16,400美元对19,400美元,P = 0.003),住院时间相似(1.4±0.1天,P = 0.931),不良事件发生率相似(7.6%对8.2%,P = 0.827)。

结论

与接受CDA的肥胖患者相比,接受ACDF的肥胖患者非常规出院率更高。虽然CDA费用更高,但在这一高风险人群中,它可能提供更好的出院结果。

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