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肥胖对颈椎间盘置换术并发症的影响。

Effects of Obesity on Cervical Disc Arthroplasty Complications.

作者信息

Berry Katherine M, Govindarajan Vaidya, Berger Connor, Maddy Krisna, Roman Roberto J Perez, Luther Evan M, Levi Allan D

机构信息

Department of Neurosurgery, University of Miami, Miller School of Medicine, Miami, FL, USA.

出版信息

Neurospine. 2023 Dec;20(4):1399-1406. doi: 10.14245/ns.2346788.394. Epub 2023 Dec 31.

Abstract

OBJECTIVE

High body mass index is a well-established modifiable comorbidity that is known to increase postoperative complications in all types of surgery, including spine surgery. Obesity is increasing in prevalence amongst the general population. As this growing population of obese patients ages, understanding how they faire undergoing cervical disc arthroplasty (CDA) is important for providing safe and effective evidence-based care for cervical degenerative pathology.

METHODS

Our study used the Healthcare Cost and Utilization Project's National Inpatient Sample to assess patients undergoing CDA comparing patient characteristics and outcomes in nonobese patients to obese patients from 2004 to 2014.

RESULTS

Our study found a significant increase in the overall utilization of CDA as a treatment modality (p = 0.012) and a statistically significant increase in obese patients undergoing CDA (p < 0.0001) from 2004 to 2014. Obesity was identified as an independent risk factor associated with increased rates of inpatient neurologic complications (odds ratio [OR], 6.99; p = 0.03), pulmonary embolus (OR, 5.41; p = 0.05), and wound infection (OR, 6.97; p < 0.001) in patients undergoing CDA from 2004 to 2014.

CONCLUSION

In patients undergoing CDA, from 2004 to 2014, obesity was identified as an independent risk factor with significantly increased rates of inpatient neurologic complications, pulmonary embolus and wound infection. Large prospective trials are needed to validate these findings.

摘要

目的

高体重指数是一种公认的可改变的合并症,已知会增加包括脊柱手术在内的所有类型手术的术后并发症。肥胖在普通人群中的患病率正在上升。随着肥胖患者群体的老龄化,了解他们接受颈椎间盘置换术(CDA)的情况对于为颈椎退行性病变提供安全有效的循证护理至关重要。

方法

我们的研究使用了医疗保健成本和利用项目的全国住院患者样本,以评估接受CDA的患者,比较2004年至2014年非肥胖患者与肥胖患者的特征和结局。

结果

我们的研究发现,从2004年到2014年,CDA作为一种治疗方式的总体使用率显著增加(p = 0.012),接受CDA的肥胖患者在统计学上显著增加(p < 0.0001)。肥胖被确定为2004年至2014年接受CDA的患者住院神经并发症发生率增加(优势比[OR],6.99;p = 0.03)、肺栓塞(OR,5.41;p = 0.05)和伤口感染(OR,6.97;p < 0.001)的独立危险因素。

结论

在2004年至2014年接受CDA的患者中,肥胖被确定为住院神经并发症、肺栓塞和伤口感染发生率显著增加的独立危险因素。需要大型前瞻性试验来验证这些发现。

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