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快速反应系统可降低院内术后心肺骤停发生率:一项回顾性研究。

A rapid response system reduces the incidence of in-hospital postoperative cardiopulmonary arrest: a retrospective study.

机构信息

Interdepartment of Critical Care Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.

Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.

出版信息

Can J Anaesth. 2018 Dec;65(12):1303-1313. doi: 10.1007/s12630-018-1200-5. Epub 2018 Aug 3.

Abstract

PURPOSE

Rapid response systems (RRSs) have been introduced into hospitals to help reduce the incidence of sudden cardiopulmonary arrest (CPA). This study evaluated whether an RRS reduces the incidence of in-hospital postoperative CPA.

METHODS

This retrospective before-and-after analysis evaluated data collected from electronic medical records during a pre-intervention (January 2008 to September 2012) and post-intervention (implementation of an RRS) interval (October 2012 to December 2016) at a single tertiary care institution. The primary outcome was a change in the rate of CPA in surgical patients recovering in a general ward. A Poisson regression analysis adjusted for the Charlson Comorbidity Index (CCI) was used to compare CPA rates during these two intervals.

RESULTS

Of the 207,054 surgical procedures performed during the study period, mean (95% confidence interval [CI]) CPA events per 10,000 cases of 7.46 (5.72 to 9.19) and 5.19 (3.85 to 6.52) were recorded before and after RRS intervention, respectively (relative risk [RR], 0.73; 97.5% CI, 0.48 to 1.13; P = 0.103). Cardiopulmonary arrest incidence was reduced during RRS operational hours of 07:00-22:00 Monday-Friday and 07:00-12:00 Saturday (RR, 0.56; 97.5% CI, 0.31 to 1.02; P = 0.027) but was unchanged when the RRS was not operational (RR, 0.86; 97.5% CI, 0.52 to 1.40; P = 0.534). The CCI-adjusted RR of CPA after RRS implementation was lower than before RRS intervention (0.63; 97.5% CI, 0.41 to 0.98; P = 0.018) but this reduction was still only apparent during RRS operational hours (RR, 0.48; 97.5% CI, 0.27 to 0.89; P = 0.008 vs RR, 0.85; 97.5% CI, 0.45 to 1.58; P = 0.55).

CONCLUSION

Implementation of an RRS reduced the incidence of postoperative CPA in patients recovering in a general ward. Furthermore, this reduction was observed only during RRS operational hours.

摘要

目的

快速反应系统(RRS)已被引入医院,以帮助降低心搏骤停(CPA)的发生率。本研究评估了 RRS 是否降低了住院术后 CPA 的发生率。

方法

本回顾性前后对照分析评估了一家三级保健机构在干预前(2008 年 1 月至 2012 年 9 月)和干预后(RRS 实施期间)(2012 年 10 月至 2016 年 12 月)电子病历中收集的数据。主要结局是比较普通病房恢复的手术患者中 CPA 的发生率变化。使用泊松回归分析调整 Charlson 合并症指数(CCI),比较这两个时间段的 CPA 发生率。

结果

在研究期间进行的 207054 例手术中,分别记录了 RRS 干预前后每 10000 例中 7.46(5.72 至 9.19)和 5.19(3.85 至 6.52)的 CPA 事件(相对风险[RR],0.73;97.5%置信区间[CI],0.48 至 1.13;P=0.103)。RRS 运行时间为周一至周五 07:00-22:00 和周六 07:00-12:00 时,CPA 发生率降低(RR,0.56;97.5%CI,0.31 至 1.02;P=0.027),而 RRS 不运行时则无变化(RR,0.86;97.5%CI,0.52 至 1.40;P=0.534)。RRS 实施后 CCI 调整的 CPA 相对风险低于 RRS 干预前(0.63;97.5%CI,0.41 至 0.98;P=0.018),但这种降低仅在 RRS 运行时间内可见(RR,0.48;97.5%CI,0.27 至 0.89;P=0.008 与 RR,0.85;97.5%CI,0.45 至 1.58;P=0.55)。

结论

实施 RRS 降低了普通病房恢复患者的术后 CPA 发生率。此外,这种降低仅在 RRS 运行时间内观察到。

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