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使用 BERTIE 对 1 型糖尿病管理进行强化结构化教育:长期随访以评估对血糖控制和生活质量指数的影响。

Intensive structured education for type 1 diabetes management using BERTIE: Long-term follow-up to assess impact on glycaemic control and quality of life indices.

机构信息

Bournemouth Diabetes & Endocrine Centre, Royal Bournemouth Hospital, Castle Lane East, Bournemouth BH7 7DW, United Kingdom.

Bournemouth Diabetes & Endocrine Centre, Royal Bournemouth Hospital, Castle Lane East, Bournemouth BH7 7DW, United Kingdom.

出版信息

Diabetes Res Clin Pract. 2018 Sep;143:275-281. doi: 10.1016/j.diabres.2018.07.034. Epub 2018 Aug 1.

DOI:10.1016/j.diabres.2018.07.034
PMID:30076871
Abstract

AIMS

Bournemouth Type 1 Intensive Education (BERTIE) is a structured education course delivered 1 day a week for 4 weeks for self-management of type 1 diabetes. BERTIE outcomes were analysed to assess long-term effectiveness: primary outcome assessed impact of BERTIE on glycaemic control, secondary outcomes assessed impact on Problem Area in Diabetes (PAID) scale, severe hypoglycaemia and diabetic ketoacidosis incidence (DKA).

METHODS

Prospectively collected outcome data from attendees included glycated haemoglobin (HbA1c), PAID, severe hypoglycaemia and DKA incidence recorded pre-course, 6 months and 1 year post-attendance, with HbA1c assessed annually at subsequent clinic visits.

RESULTS

Between 1999 and 2015, 524 people attended BERTIE with 5 year follow-up in 316 (60.3%) attendees. HbA1c was reduced from 74 ± 17 mmol/mol (8.9 ± 1.6%) at baseline to 71 ± 15 mmol/mol (8.6 ± 1.4%) at 1 year and 70 ± 15 mmol/mol (8.6 ± 1.3%) at 5 years (p < 0.0001); severe hypoglycaemia incidence reduced from 0.8 ± 2.1 to 0.4 ± 2.2 episodes/person/year at 1 year (p < 0.0001); PAID scale reduced from 23 ± 16 to 15 ± 12 (p < 0.0001) at 1 year; DKA incidence was 0.06 ± 0.34 episodes/person/year pre-course and 0.03 ± 0.21 at 1 year (p = 0.5271).

CONCLUSIONS

BERTIE outcome data demonstrate favorable biochemical and psychological outcomes supporting recommendations that structured education be provided to adults with type 1 diabetes.

摘要

目的

伯恩茅斯 1 型强化教育(BERTIE)是一种针对 1 型糖尿病自我管理的结构化教育课程,每周 1 天,为期 4 周。分析 BERTIE 的结果以评估其长期效果:主要结局评估 BERTIE 对血糖控制的影响,次要结局评估对糖尿病问题领域(PAID)量表、严重低血糖和糖尿病酮症酸中毒(DKA)发生率的影响。

方法

前瞻性收集参加者的结局数据,包括糖化血红蛋白(HbA1c)、PAID、严重低血糖和 DKA 发生率,在课程前、6 个月和 1 年后记录,并在随后的临床就诊时每年评估 HbA1c。

结果

1999 年至 2015 年间,共有 524 人参加了 BERTIE,其中 316 人(60.3%)有 5 年随访。HbA1c 从基线时的 74±17mmol/mol(8.9±1.6%)降至 1 年后的 71±15mmol/mol(8.6±1.4%)和 5 年后的 70±15mmol/mol(8.6±1.3%)(p<0.0001);严重低血糖发生率从 0.8±2.1 降至 1 年后的 0.4±2.2 次/人/年(p<0.0001);PAID 量表从 23±16 降至 1 年后的 15±12(p<0.0001);DKA 发生率在课程前为 0.06±0.34 次/人/年,1 年后为 0.03±0.21 次/人/年(p=0.5271)。

结论

BERTIE 的结果数据显示出有利的生化和心理结局,支持为 1 型糖尿病成人提供结构化教育的建议。

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