Flavonoids, Sterols and Lignans from and Their Relationship with Its Liver Activity.

The sterols β-sitostenone (), stigmast-4,6,8(14),22-tetraen-3-one (), β-sitosterol () and stigmasterol (), the aromatic derivatives antiarol () and gentisic acid (), the phenylpropanes coniferyl alcohol (), epoxyconiferyl alcohol () and ferulic acid (), the apocarotenoid vomifoliol (), the flavonoids naringenin (), 7,4'-dimethoxytaxifolin (7,4'-dimethoxydihydroquercetin, ), aromadendrin (), kaempferol (), taxifolin (dihydroquercetin, ), prunin (naringenin-7--β-d-glucoside, ), populnin (kaempferol-7--β-d-glucoside, ) and senecin (aromadendrin-7--β-d-glucoside, ) and the lignans kobusin () and pinoresinol (), were isolated from the dried bark of Spreng (Cochlospermaceae), a Mexican medicinal plant used to treat jaundice, liver ailments and hepatitis C. Fourteen of these compounds were isolated for the first time from this plant and from the genus. Compounds ⁻, ⁻, ⁻, ⁻ and have previously exhibited diverse beneficial liver activities. The presence of these compounds in correlates with the use of this Mexican medicinal plant.