Du Cong, Wang Chongdan, Zhang Yixin, Fan Lili, Wang Wei, Chen Wen, Shen Jun, Zhang Wanqi
School of Public Health, Tianjin Medical University, Tianjin 300070, China.
Wei Sheng Yan Jiu. 2018 Jul;47(4):543-547.
To investigate the iodine status of lactating women and the influence on infants during the first 24 weeks postpartum in Tianjin City.
The iodine concentration of human milk and urine were measured from 438 lactating women and their exclusive breastfeeding infants.
Significant difference was found between the levels of BMIC according to the time of collecting samples( P < 0. 001). The BMIC was lower at the 24th week postpartum with a M( P25-P75) of 123. 5 μg/L( 83. 1-177. 6 μg/L) and the level of lactating women's UIC was lower at the 4th week postpartum with the M( P25-P75) of 87 μg/L( 52-159 μg/L). Besides that, the level of infants ' UIC was lower at the 12th week postpartum with the M( P25-P75) of 191 μg/L( 130-302 μg/L). Lactating women's BMIC and UIC( r = 0. 238, P <0. 001), lactating women's BMIC and infants' UIC( r = 0. 257, P < 0. 001), lactating women's UIC and infants' UIC( r = 0. 148, P < 0. 001) were significantly positive correlated. According to different time of collecting samples, the levels of infants' UIC were significant different categorized by BMIC at 4th, 12th, 24th week postpartum( P <0. 05).
The BMIC gradually decreased during the first 24 weeks postpartum in Tianjin, but still been in the sufficient iodine status. The iodine status of lactating women can affect their infants' iodine status.
调查天津市哺乳期妇女的碘营养状况及其对产后24周内婴儿的影响。
对438名哺乳期妇女及其纯母乳喂养的婴儿进行母乳和尿液碘浓度测定。
不同采样时间的哺乳期妇女母乳碘浓度(BMIC)水平差异有统计学意义(P<0.001)。产后24周时BMIC较低,中位数M(P25-P75)为123.5μg/L(83.1-177.6μg/L);哺乳期妇女尿碘浓度(UIC)在产后4周时较低,M(P25-P75)为87μg/L(52-159μg/L)。此外,婴儿UIC在产后12周时较低,M(P25-P75)为191μg/L(130-302μg/L)。哺乳期妇女的BMIC与UIC(r=0.238,P<0.001)、哺乳期妇女的BMIC与婴儿UIC(r=0.257,P<0.001)、哺乳期妇女的UIC与婴儿UIC(r=0.148,P<0.001)均呈显著正相关。根据不同采样时间,产后第4、12、24周婴儿UIC水平按BMIC分类差异有统计学意义(P<0.05)。
天津市哺乳期妇女在产后24周内BMIC逐渐下降,但仍处于碘营养充足状态。哺乳期妇女的碘营养状况可影响其婴儿的碘营养状况。