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叶状囊肉瘤。19例病例回顾,重点关注伴发乳腺癌的情况。

Cystosarcoma phyllodes. A review of 19 cases with emphasis on the occurrence of associated breast carcinoma.

作者信息

Christensen L, Nielsen M, Madsen P M

出版信息

Acta Pathol Microbiol Immunol Scand A. 1986 Jan;94(1):35-41.

PMID:3008499
Abstract

The clinico-pathological aspects of 19 cases of cystosarcoma phyllodes (CP) were reviewed with special attention to the occurrence of associated breast carcinoma (BC). Twelve women had histologically benign, 4 had borderline and 3 malignant CP. Recurrent CP was diagnosed in 9 women within 1 to 15 years after initial treatment. Of the 19 women, 5 had associated in situ or invasive BC, 2 with the primary CP and 3 with its recurrences. In 1 case the BC was located within the confines of the CP, whereas in 4 women the CP and BC were separate lesions. The frequency of incidentally found BC in this group of women with CP does not support the hypothesis of an increased risk of BC development in women with CP.

摘要

对19例叶状囊肉瘤(CP)的临床病理特征进行了回顾,特别关注相关乳腺癌(BC)的发生情况。12名女性患有组织学上良性的CP,4名患有交界性CP,3名患有恶性CP。9名女性在初次治疗后1至15年内被诊断为复发性CP。在这19名女性中,5名患有相关的原位或浸润性BC,其中2名与原发性CP相关,3名与其复发相关。1例BC位于CP范围内,而在4名女性中,CP和BC是独立的病变。在这组患有CP的女性中偶然发现BC的频率并不支持CP女性患BC风险增加的假设。

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Acta Pathol Microbiol Immunol Scand A. 1986 Jan;94(1):35-41.
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引用本文的文献

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Unexpectedly High Coexistence Rate of /Invasive Carcinoma In Phyllodes Tumors. 10-Year Retrospective and Review Study.叶状肿瘤中浸润性癌的意外高共存率。一项10年的回顾性研究与文献综述
Eur J Breast Health. 2022 Oct 1;18(4):343-352. doi: 10.4274/ejbh.galenos.2022.2022-6-2. eCollection 2022 Oct.
2
Malignant Epithelial Transformation in Phyllodes Tumor: A Population-Based Case Series.叶状肿瘤中的恶性上皮化生:一项基于人群的病例系列研究。
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Bilateral invasive duct carcinoma, phyllodes tumor and multiple fibroadenomas of breast associated with lymph node metastases - rare coexistence.
双侧浸润性导管癌、叶状肿瘤和乳腺多发纤维腺瘤伴淋巴结转移——罕见共存情况。
Indian J Surg Oncol. 2014 Sep;5(3):186-8. doi: 10.1007/s13193-014-0338-z. Epub 2014 Jul 29.
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Borderline phyllodes tumor with an incidental invasive tubular carcinoma and lobular carcinoma in situ component: a case report.交界性叶状肿瘤伴偶然侵袭性管状癌和原位小叶癌成分:一例报告。
J Breast Cancer. 2011 Sep;14(3):237-40. doi: 10.4048/jbc.2011.14.3.237. Epub 2011 Sep 29.
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Malignant phyllodes tumour with liposarcomatous differentiation, invasive tubular carcinoma, and ductal and lobular carcinoma in situ: case report and review of the literature.伴有脂肪肉瘤样分化的恶性叶状肿瘤、浸润性导管癌及导管原位癌和小叶原位癌:病例报告及文献复习
Patholog Res Int. 2010 Jul 5;2010:501274. doi: 10.4061/2010/501274.
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Molecular analysis of phyllodes tumors reveals distinct changes in the epithelial and stromal components.叶状肿瘤的分子分析揭示了上皮和间质成分的明显变化。
Am J Pathol. 2000 Mar;156(3):1093-8. doi: 10.1016/S0002-9440(10)64977-2.