MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dow Street, DD1 5EH, UK.
Curr Biol. 2018 Aug 6;28(15):R842-R845. doi: 10.1016/j.cub.2018.06.067.
It is crucial to remove dysfunctional mitochondria and peroxisomes to prevent cellular damage. Recent work suggests that under basal conditions USP30, a deubiquitinating enzyme, works to ensure that both of these organelles are only turned over at the right time.
去除功能失调的线粒体和过氧化物酶体对于防止细胞损伤至关重要。最近的研究表明,在基础条件下,去泛素化酶 USP30 确保这两种细胞器只在适当的时候被降解。