IRISSE Laboratory (EA4075), UFR SHE, University of La Réunion, 117 rue du General Ailleret, 97430, Le Tampon, La Réunion, France.
Eur J Appl Physiol. 2018 Nov;118(11):2331-2338. doi: 10.1007/s00421-018-3959-z. Epub 2018 Aug 7.
Although walking is the most commonly recommended activity for patients with type 2 diabetes (T2D), these patients walk daily less than their healthy peers and adopt a lower self-selected speed. It has been suggested that gait alterations observed in this population could be responsible for a higher metabolic rate (MR) during walking. Thus, the aim of this study was to compare relationship between MR, the energy cost of walking per unit of distance (Cw) and self-selected walking speed in T2D patients and healthy individuals.
We measured metabolic and spatiotemporal parameters for 20 T2D patients and 20 healthy control subjects, while they walked on a treadmill at different speeds (0.50-1.75 m s) using a breath-by-breath gas analyzer and an inertial measurement unit, respectively.
Net MR was 14.3% higher for T2D patients on average across all speeds, and they preferred to walk 6.8% slower at their self-selected compared with their non-diabetics counterparts (1.33 vs. 1.42 m s, respectively; p = 0.045). Both groups naturally walked at a self-selected speed close to their minimum gross Cw per distance, with similar values of minimum gross Cw (3.53 and 3.32 J kg m in T2D patients and control subjects, respectively).
When compared with healthy subjects, T2D patients walk with a higher MR at any given speed. Thus, the slower self-selected speed observed in T2D patients seems to correspond to the speed at which their gross energy cost per distance was minimized and allows T2D patients to walk at the same intensity than healthy subjects.
尽管对于 2 型糖尿病（T2D）患者来说，步行是最常推荐的活动，但这些患者每天的步行量少于健康同龄人，且选择的速度较低。有人认为，该人群中观察到的步态改变可能是导致步行时代谢率（MR）升高的原因。因此，本研究旨在比较 T2D 患者和健康个体的 MR 与单位距离的步行能量消耗（Cw）和自选择步行速度之间的关系。
我们使用呼吸分析仪和惯性测量单元分别测量了 20 名 T2D 患者和 20 名健康对照组在不同速度（0.50-1.75 m/s）下的代谢和时空参数。
T2D 患者的平均净 MR 比所有速度都高出 14.3%，与非糖尿病患者相比，他们更喜欢以 6.8%的速度较慢地自选择行走（分别为 1.33 和 1.42 m/s；p=0.045）。两组人群都自然地以接近其最小总 Cw/距离的自选择速度行走，最小总 Cw 具有相似的值（T2D 患者和对照组分别为 3.53 和 3.32 J/kg·m）。
与健康受试者相比，T2D 患者在任何给定速度下的 MR 都较高。因此，T2D 患者观察到的较慢的自选择速度似乎与他们的总距离能量消耗最小的速度相对应，并且允许 T2D 患者以与健康受试者相同的强度行走。
