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平衡受损与年轻和老年糖尿病患者并发症的进展有关。

Impaired balance is related to the progression of diabetic complications in both young and older adults.

机构信息

Department of Metabolic Medicine, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan.

Department of Metabolic Medicine, National Hospital Organization Kumamoto Medical Center, 1-5 Ninomaru, Chuo-ku, Kumamoto 860-0008, Japan.

出版信息

J Diabetes Complications. 2017 Aug;31(8):1275-1282. doi: 10.1016/j.jdiacomp.2017.05.014. Epub 2017 Jun 4.

Abstract

AIMS

To investigate the balance ability in younger and older adults with diabetes and evaluate the associations between balance ability and microvascular complications.

METHODS

This cross-sectional observational study compared 162 participants and 177 controls with and without type 2 diabetes, respectively. Balance ability was assessed using two static (one-legged stance and postural sway area) and two dynamic (Timed Up and Go [TUG] and Functional Reach) tests. Diabetic microangiopathy was also evaluated.

RESULTS

Participants with diabetes, including both younger (<50years) and older (≥50years) participants, showed significantly worse balance ability in all four tests and were more likely to have a history of falls than the controls (all P<0.01). In all age groups, severe impairment of balance ability was associated with progression of diabetic microvascular complications. In all and older diabetic adults, a longer duration of diabetes (P=0.022) and higher TUG test score (P=0.004), and female sex (P=0.01) and higher TUG score (P=0.001), respectively, were related to a history of falls. On the other hand, among younger diabetic adults, only a non-significant association with longer duration of diabetes (P=0.066) was observed.

CONCLUSIONS

Impaired balance ability correlates with microvascular diabetic complications. Accurate assessment of balance ability in adults with diabetes could predict the risk of falls, particularly benefitting people with diabetic complications.

摘要

目的

调查糖尿病患者中年轻和老年成年人的平衡能力,并评估平衡能力与微血管并发症之间的关联。

方法

这项横断面观察性研究比较了 162 名参与者和 177 名对照者,分别患有和不患有 2 型糖尿病。使用两种静态(单腿站立和姿势摆动面积)和两种动态(计时起立和行走 [TUG] 和功能性伸展)测试来评估平衡能力。还评估了糖尿病微血管病变。

结果

患有糖尿病的参与者,包括年轻(<50 岁)和年长(≥50 岁)的参与者,在所有四项测试中的平衡能力均明显较差,并且比对照组更有可能有跌倒史(均 P<0.01)。在所有年龄组中,严重的平衡能力障碍与糖尿病微血管并发症的进展有关。在所有和年长的糖尿病患者中,糖尿病病程较长(P=0.022)和 TUG 测试得分较高(P=0.004),以及女性(P=0.01)和 TUG 得分较高(P=0.001)分别与跌倒史有关。另一方面,在年轻的糖尿病患者中,仅观察到与糖尿病病程较长的非显著关联(P=0.066)。

结论

平衡能力受损与糖尿病微血管并发症相关。在糖尿病成年人中准确评估平衡能力可以预测跌倒的风险,特别是对患有糖尿病并发症的人有益。

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