中脑边缘多巴胺投射调节伏隔核神经元中杏仁核诱发的兴奋性突触后电位：一项体内研究。
Mesolimbic dopamine projection modulates amygdala-evoked EPSP in nucleus accumbens neurons: an in vivo study.
作者信息
Yim C Y, Mogenson G J
出版信息
Brain Res. 1986 Mar 26;369(1-2):347-52. doi: 10.1016/0006-8993(86)90548-2.
PMID:3008939
Abstract
In urethane anesthetized rats, excitatory postsynaptic potential (EPSP) recorded intracellularly from nucleus accumbens neurons following stimulation of the amygdala was attenuated by repetitive stimulation of the ventral tegmental area (VTA). VTA stimulation also depolarized the resting membrane potential of accumbens neurons. Attenuation of the EPSP and membrane depolarization were frequently dissociated but both were blocked by haloperidol, a dopamine antagonist.
摘要
在氨基甲酸乙酯麻醉的大鼠中，刺激杏仁核后从伏隔核神经元细胞内记录到的兴奋性突触后电位（EPSP），在反复刺激腹侧被盖区（VTA）后减弱。VTA刺激还使伏隔核神经元的静息膜电位去极化。EPSP的减弱和膜去极化常不相关，但两者均被多巴胺拮抗剂氟哌啶醇阻断。
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