Ranjan Rupesh, Priyamvada Richa, Jha Gyanendra Kumar, Chaudhury Suprakash
Department of Psychiatry, BMHRC, Bhopal, Madhya Pradesh, India.
Department of Psychology, Patna University, Patna, India.
Ind Psychiatry J. 2017 Jul-Dec;26(2):178-182. doi: 10.4103/ipj.ipj_86_14.
Depressed patients are preoccupied with unhappy thoughts which reduce their capacity to focus on attention, memory, and other cognitive performance.
The aim of this study is to assess neuropsychological deficits in elderly depressive and compare it with matched normal controls.
After consideration of inclusion and exclusion criteria, the sample of 30 elderly depressive patients diagnosed on the basis of International Classification of Diseases, Tenth Edition criteria and 30 normal controls were selected. The selection of sample was by purposive sampling from private psychiatric clinic of Bhopal. The age range of sample was 60 years and above. All participants were administered the Geriatric Depression Scale, and the Luria-Nebraska Neuropsychological Battery-1 (LNNB form-1).
On the Geriatric Depression Scale, 21 patients were at mild level and nine patients were at severe level of depression. None of the normal controls were depressed. On LNNB form-1, depressive patients showed significant elevation on receptive speech, arithmetic, memory, reading, writing, and expressive speech as compared to normal controls.
Older depressive patients showed significantly more neurocognitive deficits as compared to normal controls. It is important that these deficits are identified and addressed for the holistic treatment of late-onset depression.
抑郁症患者被不愉快的想法所困扰，这降低了他们集中注意力、记忆及其他认知表现的能力。
本研究旨在评估老年抑郁症患者的神经心理学缺陷，并将其与匹配的正常对照组进行比较。
在考虑纳入和排除标准后，选取了30例根据《国际疾病分类》第十版标准诊断的老年抑郁症患者样本和30例正常对照。样本通过从博帕尔的私人精神病诊所进行目的抽样选取。样本年龄范围在60岁及以上。所有参与者均接受了老年抑郁量表和鲁利亚-内布拉斯加神经心理成套测验-1（LNNB-1型）测试。
在老年抑郁量表上，21例患者处于轻度抑郁水平，9例患者处于重度抑郁水平。正常对照组均无抑郁。在LNNB-1型测试中，与正常对照组相比，抑郁症患者在接受性言语、算术、记忆、阅读、书写和表达性言语方面有显著升高。
与正常对照组相比，老年抑郁症患者表现出明显更多的神经认知缺陷。识别并解决这些缺陷对于迟发性抑郁症的整体治疗很重要。
