Daltro Carla, Gregorio Paloma Baiardi, Alves Erivaldo, Abreu Maurício, Bomfim Daniel, Chicourel Maria Helena, Araújo Leila, Cotrim Helma P
Bahiana School of Medicine and Public Health, Department of Internal Medicine, Bahia, Brazil.
Obes Surg. 2007 Jun;17(6):809-14. doi: 10.1007/s11695-007-9147-6.
Obesity is the most important risk factor for obstructive sleep apnea. It is estimated that 70% of sleep apnea patients are obese. In the morbidly obese, the prevalence may reach 80% in men and 50% in women. The aim of this study was to determine the prevalence and severity of sleep apnea in a group of morbidly obese patients, leading to bariatric surgery.
In a cross-sectional study developed in Bahia, northeastern Brazil. 108 patients (78 women and 30 men) from the Obesity Treatment and Surgery Center--"Núcleo de Tratamento e Cirurgia da Obesidade" underwent standard polysomnography. Patients with an apnea-hypopnea index (AHI) > or = 5 events/hour were considered apneic.
Mean +/- SD for age and BMI were 37.1 +/- 10.2 years and 45.2 +/- 5.4 kg/m2, respectively. The calculated AHI ranged widely from 2.5 to 128.9 events/hour. Sleep apnea was detected in 93.6% of the sample, wherein 35.2% had mild, 30.6% moderate and 27.8% severe apnea. Oxyhemoglobin desaturation was directly related to the AHI and was more severe in men.
There was a high frequency of sleep apnea in this group of morbidly obese patients, for whom it was very important to request polysomnography, thus enabling therapeutic management and prognostication.
肥胖是阻塞性睡眠呼吸暂停最重要的危险因素。据估计，70%的睡眠呼吸暂停患者肥胖。在病态肥胖者中，男性患病率可达80%，女性为50%。本研究的目的是确定一组准备接受减肥手术的病态肥胖患者中睡眠呼吸暂停的患病率和严重程度。
在巴西东北部巴伊亚州开展的一项横断面研究中，肥胖治疗与手术中心——“肥胖治疗与手术核心组”的108例患者（78例女性和30例男性）接受了标准多导睡眠图检查。呼吸暂停低通气指数（AHI）≥5次/小时的患者被视为呼吸暂停患者。
年龄和体重指数（BMI）的均值±标准差分别为37.1±10.2岁和45.2±5.4kg/m²。计算得出的AHI范围广泛，从2.5至128.9次/小时。93.6%的样本检测到睡眠呼吸暂停，其中35.2%为轻度，30.6%为中度，27.8%为重度呼吸暂停。氧合血红蛋白饱和度降低与AHI直接相关，且在男性中更严重。
这组病态肥胖患者中睡眠呼吸暂停的发生率很高，对他们进行多导睡眠图检查非常重要，这样能够进行治疗管理和预后评估。
