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成功实现部分闭塞性基底动脉开窗的血管内再通。

Successful endovascular recanalization of a partially occluded basilar artery fenestration.

作者信息

Meinel Thomas Raphael, Pult Frauke, Gralla Jan, Arnold Marcel, Bassetti Claudio, Jung Simon

机构信息

1 Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

2 University Institute of Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

出版信息

Interv Neuroradiol. 2019 Feb;25(1):44-46. doi: 10.1177/1591019918793340. Epub 2018 Aug 9.

Abstract

A 76-year-old man with a history of arterial hypertension, obstructive sleep apnea, dyslipidemia, family history of cardiovascular events, prestroke and overweight presented 90 minutes after acute onset of right-sided sensorimotor hemiparesis, hemiataxia and dysarthria (National Institutes of Health Stroke Scale (NIHSS) 9/42). Magnetic resonance imaging (MRI) revealed a pontine ischemia and MR angiography showed a thrombus in the middle to distal portion of the basilar artery. Owing to the location, an occlusion of one lumen of a fenestrated basilar artery was suspected. Fearing the risk of peripheral dislocation, intravenous thrombolysis was withheld after an interdisciplinary discussion and direct endovascular thrombectomy (Solitaire stent retriever) was successfully performed by passing the stent retriever specifically through the affected lumen and between the thrombus and the vascular wall, which would normally be avoided. Angiography after complete reperfusion (Thrombolysis in Cerebral Infarction grade 3) confirmed a fenestration in the middle to distal portion of the basilar artery where the thrombus was initially located (blue and green arrow). Follow-up MRI after 24 hours showed only minimal ischemic damage in the left pontine area, and the patient was discharged home with ambulatory physiotherapy for residual minimal gait disturbance (NIHSS 0).

摘要

一名76岁男性,有动脉高血压、阻塞性睡眠呼吸暂停、血脂异常病史,有心血管事件家族史,曾有中风史且超重,在急性出现右侧感觉运动性偏瘫、半身共济失调和构音障碍90分钟后就诊(美国国立卫生研究院卒中量表(NIHSS)评分9/42)。磁共振成像(MRI)显示脑桥缺血,磁共振血管造影显示基底动脉中远端有血栓。由于病变位置,怀疑是开窗型基底动脉的一个管腔闭塞。经多学科讨论后,因担心外周移位风险,未进行静脉溶栓,而是成功实施了直接血管内血栓切除术(Solitaire支架取栓器),具体操作是使支架取栓器穿过受影响的管腔并置于血栓与血管壁之间,而这通常是要避免的。完全再灌注后(脑梗死溶栓分级3级)的血管造影证实,血栓最初所在的基底动脉中远端有一个开窗(蓝色和绿色箭头)。24小时后的随访MRI显示左脑桥区域仅有轻微缺血损伤,患者出院回家,针对残留的轻微步态障碍接受门诊物理治疗(NIHSS评分0)。

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本文引用的文献

1
Fenestrations of the basilar artery demonstrated on magnetic resonance angiograms: an analysis of 212 cases.
Interv Neuroradiol. 2013 Dec;19(4):461-5. doi: 10.1177/159101991301900409. Epub 2013 Dec 18.
2
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J Neuroimaging. 2014 Nov-Dec;24(6):607-609. doi: 10.1111/jon.12069. Epub 2013 Nov 19.
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Lancet Neurol. 2011 Nov;10(11):1002-14. doi: 10.1016/S1474-4422(11)70229-0.

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