Chen Xiao, Xu Hai-Tao, Zhang Hong-Jun, Chen Jing
Department of Orthopedic Surgery, The First People's Hospital of Neijiang, Sichuan Department of Orthopedic Surgery, Yongchuan Hospital, Chongqing Medical University, Chongqing Department of Neonatology, The First People's Hospital of Neijiang, Sichuan, China.
Medicine (Baltimore). 2018 Aug;97(32):e11799. doi: 10.1097/MD.0000000000011799.
Numerous studies have compared suprapatellar (SP) nailing to infrapatellar (IP) nailing for treatment of tibial shaft fractures; however, the best strategy remains controversial. The aim of this meta-analysis is to assess whether SP or IP nailing is more effective for tibial shaft fractures in adults.
Literature searches of PubMed, Embase, OVID, Cochrane Library, Web of Science, Chinese Biomedical Literature, Wanfang, Weipu Journal, and CNKI databases were performed up to July 2017. Only randomized controlled trials (RCTs) comparing SP versus IP intramedullary nailing for tibial shaft fractures were included. Data collection and extraction, quality assessment, and data analyses were performed according to the Cochrane standards.
Twelve RCTs were selected for analysis. SP intramedullary nailing reduced knee joint pain, visual analog score, fluoroscopy time, and sagittal angle, resulting in better Harris hip score, Lysholm knee score, short-form 36 questionnaire, range of motion, and rates of "excellent" and "good" outcome. There were no significant differences in operative time, blood loss, length of hospital stay, union time, and coronal angle between groups.
The present meta-analysis indicates that SP intramedullary nailing has obvious advantages over IP intramedullary nailing for treatment of tibial shaft fractures in adults. However, owing to the low-quality evidence currently available, additional high-quality RCTs are needed to confirm these findings.
众多研究已将胫骨近端髓内钉固定术(SP)与胫骨远端髓内钉固定术(IP)用于治疗胫骨干骨折进行了比较;然而,最佳策略仍存在争议。本荟萃分析的目的是评估SP或IP髓内钉固定术对成人胫骨干骨折是否更有效。
截至2017年7月,对PubMed、Embase、OVID、Cochrane图书馆、科学网、中国生物医学文献数据库、万方数据库、维普期刊数据库和中国知网数据库进行了文献检索。仅纳入比较SP与IP髓内钉固定术治疗胫骨干骨折的随机对照试验(RCT)。根据Cochrane标准进行数据收集与提取、质量评估及数据分析。
选取12项RCT进行分析。SP髓内钉固定术可减轻膝关节疼痛、视觉模拟评分、透视时间及矢状角,从而使Harris髋关节评分、Lysholm膝关节评分、简明健康状况调查问卷、活动范围以及“优”和“良”结局的发生率更高。两组在手术时间、失血量、住院时间、骨折愈合时间及冠状角方面无显著差异。
本荟萃分析表明,对于成人胫骨干骨折的治疗,SP髓内钉固定术相较于IP髓内钉固定术具有明显优势。然而,由于目前可用证据质量较低,需要更多高质量的RCT来证实这些发现。