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电子筛查和简短干预对医院门诊环境中成年人危险或有害饮酒的影响:一项随机、双盲、对照试验。

Effect of electronic screening and brief intervention on hazardous or harmful drinking among adults in the hospital outpatient setting: A randomized, double-blind, controlled trial.

机构信息

School of Medicine and Public Health, The University of Newcastle, University Drive, Callaghan, NSW, 2308, Australia.

School of Medicine and Public Health, The University of Newcastle, University Drive, Callaghan, NSW, 2308, Australia.

出版信息

Drug Alcohol Depend. 2018 Oct 1;191:78-85. doi: 10.1016/j.drugalcdep.2018.06.030. Epub 2018 Aug 2.

Abstract

BACKGROUND

Most trials of electronic alcohol screening and brief intervention (e-SBI) have been conducted in young people. The aim of this study was to evaluate the effect of e-SBI in adults with hazardous or harmful drinking.

METHODS

This individually randomized, parallel, two-group, double-blind controlled trial was conducted in the outpatient department of a large public hospital in Australia. Consenting adults who scored 5-9 on the AUDIT-C (837/3225; 26%) were randomized in a 1:1 ratio by computer to screening alone (442/837; 53%) or to 10 min of assessment and personalized feedback on their alcohol consumption (comparisons with medical guidelines and age and sex-specific norms), peak blood alcohol concentration, expenditure on alcohol, and risk of alcohol dependence (395/837; 47%). The two primary outcomes, assessed six months after randomization, were the number of standard drinks (10 g ethanol) consumed by participants in the last seven days and their AUDIT score.

RESULTS

693/837 (83%) and 635/837 (76%) participants were followed-up at 6 and 12 months, respectively. There was no statistically significant difference between the groups in the median number of standard drinks consumed in the last seven days (intervention: 12; control: 10.5; rate ratio, 1.12 [95% confidence interval, 0.96-1.31]; P = .17) or in their median AUDIT score (intervention: 7; control: 7; mean difference, 0.28 [-0.42 to 0.98]; P = .44).

CONCLUSION

These results do not support the implementation of an e-SBI program comprising personalized feedback and normative feedback for adults with hazardous or harmful drinking in the hospital outpatient setting.

摘要

背景

大多数电子酒精筛查和简短干预(e-SBI)试验都是在年轻人中进行的。本研究旨在评估 e-SBI 对有危险或有害饮酒行为的成年人的效果。

方法

这是一项在澳大利亚一家大型公立医院的门诊部门进行的个体随机、平行、两组、双盲对照试验。符合条件的成年人 AUDIT-C 评分为 5-9 分(837/3225;26%),通过计算机以 1:1 的比例随机分为筛查组(442/837;53%)或 10 分钟评估和个性化反馈其饮酒情况(与医学指南和年龄及性别特定标准比较)、血液酒精浓度峰值、酒精支出和酒精依赖风险(395/837;47%)。主要结局是在随机分组后 6 个月评估的参与者在过去 7 天内饮用的标准饮品数量(10g 乙醇)和他们的 AUDIT 评分。

结果

837 名参与者中有 693 名(83%)和 635 名(76%)在 6 个月和 12 个月时进行了随访。两组在过去 7 天内饮用的标准饮品中位数(干预组:12;对照组:10.5;率比,1.12[95%置信区间,0.96-1.31];P=0.17)或 AUDIT 评分中位数(干预组:7;对照组:7;平均差异,0.28[-0.42 至 0.98];P=0.44)均无统计学显著差异。

结论

这些结果不支持在医院门诊环境中为有危险或有害饮酒行为的成年人实施包含个性化反馈和规范反馈的 e-SBI 计划。

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