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谷胱甘肽作用于致癌性铬（VI）会产生寿命相对较长的铬（V）物种。

Relatively long-lived chromium(V) species are produced by the action of glutathione on carcinogenic chromium(VI).

作者信息

Goodgame D M, Joy A M

出版信息

J Inorg Biochem. 1986 Mar;26(3):219-24. doi: 10.1016/0162-0134(86)80044-7.

DOI:10.1016/0162-0134(86)80044-7
PMID:3009713
Abstract

X-Band EPR studies on aqueous solutions of potassium dichromate and gamma-L-glutamyl-L-cysteinylglycine (reduced glutathione) at pH 6-8 have shown the formation of several relatively long-lived chromium(V) species. The major species formed at high glutathione:Cr(VI) ratios is characterised by an EPR band at g = 1.995, but the dominant complex at equimolar ratios produces a signal at g = 1.985.

摘要

对重铬酸钾水溶液以及γ-L-谷氨酰-L-半胱氨酰甘氨酸（还原型谷胱甘肽）在pH值6 - 8条件下进行的X波段电子顺磁共振（EPR）研究表明，形成了几种寿命相对较长的五价铬物种。在高谷胱甘肽:六价铬比例下形成的主要物种的特征是在g = 1.995处有一个EPR谱带，但等摩尔比例下的主要配合物在g = 1.985处产生信号。

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