Epstein-Barr virus (EBV) infection in early childhood is usually asymptomatic or associated with symptoms common to many other viral infections, such as pharyngitis, bronchitis or enteritis. Typical infectious mononucleosis, as seen in young adult patients, is rare in early childhood. There is also a lower rate of heterophil antibody responses in young children. Many complications of the infection are known, and many atypical manifestations can be identified as EBV-associated using modern EBV-specific serological methods. The problems of EBV infection during gestation and the neonatal period are described and the chronic and persistent infections, as well as the lymphoproliferative syndromes associated with EBV infection, are particularly taken into consideration.
幼儿期的爱泼斯坦-巴尔病毒(EBV)感染通常无症状,或与许多其他病毒感染常见的症状相关,如咽炎、支气管炎或肠炎。典型的传染性单核细胞增多症,如在年轻成年患者中所见,在幼儿期很少见。幼儿中嗜异性抗体反应的发生率也较低。已知该感染有许多并发症,使用现代EBV特异性血清学方法可将许多非典型表现鉴定为与EBV相关。本文描述了妊娠期和新生儿期EBV感染的问题,并特别考虑了慢性和持续性感染以及与EBV感染相关的淋巴增殖综合征。