• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新诊断出患有艾滋病并伴有神经梅毒、卡波西肉瘤、全血细胞减少症、口腔念珠菌病和铜绿假单胞菌肺炎:我们不该再看到这种情况了。

Newly diagnosed AIDS with neurosyphilis, Kaposi sarcoma, pancytopenia, oropharyngeal candidiasis, and pseudomonal pneumonia: We shouldn't be seeing this anymore.

作者信息

Yunina Daria S, Elkayam Natalie, Patel Shanti, Okoli Fidelis, Chapnick Edward, Hecht Melvyn

机构信息

Internal Medicine, Department of Medicine, Maimonides Medical Center, Brooklyn, NY, USA.

Infectious Disease, Department of Medicine, Maimonides Medical Center, Brooklyn, NY, USA.

出版信息

IDCases. 2018 Jul 12;13:e00426. doi: 10.1016/j.idcr.2018.e00426. eCollection 2018.

DOI:10.1016/j.idcr.2018.e00426
PMID:30101071
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6076223/
Abstract

The incidence of new human immunodeficiency virus (HIV) infections is declining and is half of what it was in the mid 1990s. We present a case of newly diagnosed HIV with acquired immune deficiency syndrome (AIDS), Neurosyphilis, Kaposi Sarcoma, and multiple opportunistic infections. Although this type of patient was not uncommon in the pre-antiretroviral era, we do not often see such a constellation of conditions in a single individual. The significance of this case lies not in the diagnosis, but rather in the number of the diagnoses and the thought process used to attain them.

摘要

新的人类免疫缺陷病毒(HIV)感染发病率正在下降,目前仅为20世纪90年代中期的一半。我们报告一例新诊断的HIV感染合并获得性免疫缺陷综合征(AIDS)、神经梅毒、卡波西肉瘤和多种机会性感染的病例。虽然这类患者在抗逆转录病毒治疗时代之前并不罕见,但我们很少在单个个体中看到如此多病症的组合。该病例的意义不在于诊断本身,而在于诊断的数量以及得出这些诊断的思维过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db72/6076223/d63e446a8d51/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db72/6076223/742c37f43caf/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db72/6076223/d63e446a8d51/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db72/6076223/742c37f43caf/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db72/6076223/d63e446a8d51/gr2.jpg

相似文献

1
Newly diagnosed AIDS with neurosyphilis, Kaposi sarcoma, pancytopenia, oropharyngeal candidiasis, and pseudomonal pneumonia: We shouldn't be seeing this anymore.新诊断出患有艾滋病并伴有神经梅毒、卡波西肉瘤、全血细胞减少症、口腔念珠菌病和铜绿假单胞菌肺炎:我们不该再看到这种情况了。
IDCases. 2018 Jul 12;13:e00426. doi: 10.1016/j.idcr.2018.e00426. eCollection 2018.
2
Beta-interferon therapy in patients with poor-prognosis Kaposi sarcoma related to the acquired immunodeficiency syndrome (AIDS). A phase II trial with preliminary evidence of antiviral activity and low incidence of opportunistic infections.β-干扰素治疗与获得性免疫缺陷综合征(AIDS)相关的预后不良的卡波西肉瘤患者。一项II期试验,有抗病毒活性的初步证据且机会性感染发生率低。
Ann Intern Med. 1990 Apr 15;112(8):582-9. doi: 10.7326/0003-4819-112-8-582.
3
Trends in the incidence of outcomes defining acquired immunodeficiency syndrome (AIDS) in the Multicenter AIDS Cohort Study: 1985-1991.多中心艾滋病队列研究中定义获得性免疫缺陷综合征(AIDS)的结局发生率趋势:1985 - 1991年
Am J Epidemiol. 1993 Feb 15;137(4):423-38. doi: 10.1093/oxfordjournals.aje.a116691.
4
Declining incidence of AIDS-defining opportunistic illnesses: results from 16 years of population-based AIDS surveillance.艾滋病定义性机会性感染发病率下降:基于人群的艾滋病监测 16 年的结果。
AIDS. 2013 Feb 20;27(4):597-605. doi: 10.1097/QAD.0b013e32835b0fa2.
5
Aggressive conjunctival Kaposi sarcoma as the initial manifestation of acquired immunodeficiency syndrome.侵袭性结膜卡波西肉瘤作为获得性免疫缺陷综合征的初始表现。
Am J Ophthalmol Case Rep. 2020 Jul 16;19:100832. doi: 10.1016/j.ajoc.2020.100832. eCollection 2020 Sep.
6
Acquired immune deficiency syndrome-related epidemic Kaposi sarcoma.获得性免疫缺陷综合征相关的流行性卡波西肉瘤
Dermatol Online J. 2018 Dec 15;24(12):13030/qt344610w2.
7
An Uncommon Presentation of Extrahepatic Cholestasis due to Single Biliary Stricture From Kaposi Sarcoma.卡波西肉瘤导致单一胆管狭窄引起的肝外胆汁淤积的罕见表现。
Cureus. 2020 Jun 29;12(6):e8913. doi: 10.7759/cureus.8913.
8
Acquired Immune Deficiency Syndrome-Associated Kaposi Sarcoma in a Child Presenting as a Solitary Plantar Hyperkeratotic Plaque.一名儿童获得性免疫缺陷综合征相关的卡波西肉瘤,表现为孤立性足底角化过度斑块。
J Cutan Med Surg. 2017 Jul/Aug;21(4):348-350. doi: 10.1177/1203475417698696. Epub 2017 Mar 13.
9
Changes in survival after acquired immunodeficiency syndrome (AIDS): 1984-1991.获得性免疫缺陷综合征(艾滋病)患者生存率的变化:1984 - 1991年
Am J Epidemiol. 1993 Dec 1;138(11):952-64. doi: 10.1093/oxfordjournals.aje.a116815.
10
Oral Kaposi sarcoma: a case of immune reconstitution inflammatory syndrome.口腔卡波西肉瘤:一例免疫重建炎症综合征病例。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Jul;108(1):70-5. doi: 10.1016/j.tripleo.2009.02.035. Epub 2009 May 22.

本文引用的文献

1
Pulmonary Kaposi Sarcoma: An Uncommon Cause of Respiratory Failure in the Era of Highly Active Antiretroviral Therapy-Case Report and Review of the Literature.肺卡波西肉瘤:高效抗逆转录病毒治疗时代呼吸衰竭的罕见病因——病例报告及文献综述
Case Rep Infect Dis. 2016;2016:9354136. doi: 10.1155/2016/9354136. Epub 2016 Oct 30.
2
Syphilis and HIV co-infection. Epidemiology, treatment and molecular typing of Treponema pallidum.梅毒与艾滋病毒合并感染。梅毒螺旋体的流行病学、治疗及分子分型
Dan Med J. 2015 Dec;62(12):B5176.
3
Frequency and Spectrum of Unexpected Clinical Manifestations of Primary HIV-1 Infection.
原发性 HIV-1 感染的意外临床表现的频率和频谱。
Clin Infect Dis. 2015 Sep 15;61(6):1013-21. doi: 10.1093/cid/civ398. Epub 2015 May 19.
4
Progressive outer retinal necrosis: manifestation of human immunodeficiency virus infection.进行性外层视网膜坏死:人类免疫缺陷病毒感染的表现
BMJ Case Rep. 2015 May 6;2015:bcr2014207344. doi: 10.1136/bcr-2014-207344.
5
Etiology, diagnosis and treatment of infectious esophagitis.感染性食管炎的病因、诊断与治疗
Prz Gastroenterol. 2013;8(6):333-7. doi: 10.5114/pg.2013.39914. Epub 2013 Dec 30.
6
Pneumocystis pneumonia in a non-HIV patient on chronic corticosteroid therapy: a question of prophylaxis.接受慢性皮质类固醇治疗的非HIV患者的肺孢子菌肺炎:预防问题
BMJ Case Rep. 2013 Mar 1;2013:bcr2012007912. doi: 10.1136/bcr-2012-007912.
7
HIV-Tuberculosis: A Study of Chest X-Ray Patterns in Relation to CD4 Count.HIV 与结核病:一项关于胸部 X 光片模式与 CD4 细胞计数关系的研究。
N Am J Med Sci. 2012 May;4(5):221-5. doi: 10.4103/1947-2714.95904.
8
What Three Wise Men have to say about diagnosis.三位智者对诊断的看法。
BMJ. 2011 Dec 20;343:d7769. doi: 10.1136/bmj.d7769.
9
Otosyphilis and HIV: therapeutic dilemma and outcome of treatment.耳梅毒与艾滋病病毒:治疗困境与治疗结果
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.01.2009.1464. Epub 2009 Oct 14.
10
Neurosyphilis presenting with dementia, chronic chorioretinitis and adverse reactions to treatment: a case report.以痴呆、慢性脉络膜视网膜炎及治疗不良反应为表现的神经梅毒:一例报告
Cases J. 2009 Sep 1;2:8334. doi: 10.4076/1757-1626-2-8334.