McKenzie Bruce John, Loock J W
Tygerberg Academic Hospital, Otorhinolaryngology, Medical Specialist Center, 8B Carinus Street, Kuils River, Cape Town, Western Cape, 7580, South Africa.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.01.2009.1464. Epub 2009 Oct 14.
We present a case report and review the world literature concerning otosyphilis, particularly with reference to the HIV positive patient. Our patient received two separate courses of treatment for otosyphilis. A course of intramuscular penicillin and oral prednisone resulted in no improvement in his hearing thresholds. A subsequent course of intravenous penicillin and oral prednisone resulted in an improvement of 79 db in his three frequency pure tone average. Otosyphilis is one of the rare causes of treatable sensorineural hearing loss. HIV has been shown to increase the severity and the progression of luetic ear disease. This case reveals that the optimal treatment remains a 10 day course of intravenous penicillin and oral prednisone.
我们报告了一例病例，并回顾了有关耳梅毒的世界文献，特别是针对艾滋病毒阳性患者。我们的患者接受了两个独立疗程的耳梅毒治疗。一个疗程的肌肉注射青霉素和口服泼尼松对其听力阈值没有改善。随后的静脉注射青霉素和口服泼尼松疗程使其三个频率的纯音平均提高了79分贝。耳梅毒是可治疗的感音神经性听力损失的罕见原因之一。已证明艾滋病毒会增加梅毒性耳部疾病的严重程度和进展。该病例表明，最佳治疗方案仍然是静脉注射青霉素和口服泼尼松的10天疗程。
