Department of Ultrasound, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China.
Department of Ultrasound, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Clin Chim Acta. 2018 Nov;486:291-297. doi: 10.1016/j.cca.2018.08.012. Epub 2018 Aug 11.
The morbidity of cesarean scar pregnancy (CSP) has shown an obvious ascending tendency with the increase of cesarean delivery in China and other countries. The timely diagnosis and treatment of CSP currently relies on medical imaging technology. In this article, we analyzed and compare the imaging methods in diagnosis of CSP. The imaging methods to diagnose CSP include traditional two-dimensional color/power Doppler ultrasound (2D-US), three-dimensional color/power Doppler ultrasound (3D-US), contrast-enhanced ultrasound (CEUS), and Magnetic Resonance Imaging (MRI). 2D-US provides important information including the location and size of gestational sac (GS), embryo with or without heart activity, and the relationship between the GS and scar. It can also divide CSP into different types, which are convenient for the choice of clinical treatment. CEUS can observe the perfusion of CSP in real-time, the arrival time of GS in CSP is earlier than that of the myometrium. It provides reliable evidence for diagnosis and evaluation of the treatment of CSP, which is helpful for making treatment plans and post-treatment follow-up. Combined use of ultrasound and CEUS could be a problem-solving method for CSP when conventional ultrasound is often inconclusive. Ultrasound has been accepted as the first-line imaging method and an important guiding method for CSP, supervising local methotrexate injection and curettage.
剖宫产术后子宫瘢痕妊娠(CSP)的发病率在中国和其他国家随着剖宫产率的增加呈现明显上升趋势。CSP 的及时诊断和治疗目前依赖于医学影像学技术。本文分析并比较了 CSP 的诊断影像学方法。诊断 CSP 的影像学方法包括传统的二维彩色/能量多普勒超声(2D-US)、三维彩色/能量多普勒超声(3D-US)、超声造影(CEUS)和磁共振成像(MRI)。2D-US 提供了包括妊娠囊(GS)的位置和大小、胚胎是否有心搏以及 GS 与瘢痕之间关系等重要信息。它还可以将 CSP 分为不同类型,便于临床治疗方案的选择。CEUS 可以实时观察 CSP 的灌注情况,GS 到达 CSP 的时间早于子宫肌层。它为 CSP 的诊断和治疗评估提供了可靠的证据,有助于制定治疗计划和治疗后的随访。当常规超声检查结果不确定时,超声联合 CEUS 可能是解决 CSP 问题的一种方法。超声已被接受为 CSP 的一线成像方法和重要的指导方法,可用于监测局部甲氨蝶呤注射和刮宫。