Medical Ethics and Law Research Center, Shahid Beheshti University of Medical Sciences, Tehran 88777539, Iran.
Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran 22439789, Iran.
Int J Mol Sci. 2018 Aug 10;19(8):2361. doi: 10.3390/ijms19082361.
In this critical review, plant sources used as effective antibacterial agents against infections are carefully described. The main intrinsic bioactive molecules, responsible for the observed effects are also underlined and their corresponding modes of action specifically highlighted. In addition to traditional uses as herbal remedies, in vitro and in vivo studies focusing on plant extracts and isolated bioactive compounds with anti- activity are also critically discussed. Lastly, special attention was also given to plant extracts with urease inhibitory effects, with emphasis on involved modes of action.
在这篇评论中，我们仔细描述了用于治疗感染的具有抗菌作用的植物来源。强调了主要的内源性生物活性分子，以及它们的作用机制。除了作为草药的传统用途外，还对具有抗活性的植物提取物和分离的生物活性化合物的体外和体内研究进行了讨论。最后，还特别关注了具有脲酶抑制作用的植物提取物，并强调了其作用机制。
