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用于骨植入研究的羟基磷灰石-虾壳纳米复合材料薄膜的电泳沉积。

Electrophoretic deposition of hydroxyapatite-shrimp crusts nanocomposite thin films for bone implant studies.

机构信息

Laser Physics Division, Applied Science Department, University of Technology, Baghdad, Iraq.

出版信息

IET Nanobiotechnol. 2018 Sep;12(6):714-721. doi: 10.1049/iet-nbt.2017.0272.

Abstract

Hydroxyapatite-shrimp crusts nanocomposite thin films were deposited on titanium substrates by electrophoretic technique, under different preparation conditions, for bone implant applications. Fourier transform infrared spectrometer, atomic force microscope, X-ray diffraction (XRD), optical microscope, and scanning electron microscope were employed to characterise the synthesised films. Vickers' micro-hardness measurements revealed a value of 502 HV for the hydroxyapatite films and 314.55 HV for the nanocomposite films. XRD results confirmed the polycrystalline nature of the hydroxyapatite and hydroxyapatite-shrimp nanocomposite films. The in-vitro bioactivity test of the synthesised films in simulated body fluid showed very low dissolution rate. Antibacterial activity of synthesised films was investigated against bacteria.

摘要

采用电泳技术在钛基体上沉积羟磷灰石-虾壳纳米复合薄膜,用于骨植入应用,在不同的制备条件下进行。傅里叶变换红外光谱仪、原子力显微镜、X 射线衍射(XRD)、光学显微镜和扫描电子显微镜用于表征合成薄膜。维氏显微硬度测量显示羟磷灰石薄膜的硬度值为 502 HV,纳米复合薄膜的硬度值为 314.55 HV。XRD 结果证实了羟磷灰石和羟磷灰石-虾壳纳米复合薄膜的多晶性质。在模拟体液中对合成薄膜的体外生物活性测试表明其溶解速率非常低。研究了合成薄膜对细菌的抗菌活性。

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