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欧盟/欧洲经济区国家急性医疗机构获得性肺炎:2011 年至 2012 年一项现况调查数据分析。

Healthcare-associated pneumonia in acute care hospitals in European Union/European Economic Area countries: an analysis of data from a point prevalence survey, 2011 to 2012.

机构信息

Unit of Healthcare-associated Infections, Surveillance of Antibiotic Resistance and Consumption, Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.

Surveillance and Response Support Unit, European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.

出版信息

Euro Surveill. 2018 Aug;23(32). doi: 10.2807/1560-7917.ES.2018.23.32.1700843.

Abstract

An aim of the ECDC point prevalence survey (PPS) in European Union/European Economic Area acute care hospitals was to acquire standardised healthcare-associated infections (HAI) data. We analysed one of the most common HAIs in the ECDC PPS, healthcare-associated pneumonia (HAP). Standardised HAI case definitions were provided and countries were advised to recruit nationally representative subsets of hospitals. We calculated 95% confidence intervals (CIs) around prevalence estimates and adjusted for clustering at hospital level. Of 231,459 patients in the survey, 2,902 (1.3%; 95% CI: 1.2-1.3) fulfilled the case definition for a HAP. HAPs were most frequent in intensive care units (8.1%; 95% CI: 7.4-8.9) and among patients intubated on the day of the survey (15%; 95% CI: 14-17; n = 737 with HAP). The most frequently reported microorganism was (17% of 1,403 isolates), followed by us (12%) and spp. (12%). Antimicrobial resistance was common among isolated microorganisms. The most frequently prescribed antimicrobial group was penicillins, including combinations with beta-lactamase inhibitors. HAPs occur regularly among intubated and non-intubated patients, with marked differences between medical specialities. HAPs remain a priority for preventive interventions, including surveillance. Our data provide a reference for future prevalence of HAPs at various settings.

摘要

欧洲疾病预防控制中心(ECDC)在欧盟/欧洲经济区急性护理医院进行的现患率调查(PPS)旨在获取标准化的医疗保健相关感染(HAI)数据。我们分析了 ECDC PPS 中最常见的 HAI 之一——医院获得性肺炎(HAP)。提供了标准化的 HAI 病例定义,并建议各国招募具有代表性的医院子集。我们计算了流行率估计值的 95%置信区间(CI),并对医院层面的聚类进行了调整。在调查的 231,459 名患者中,有 2,902 名(1.3%;95%CI:1.2-1.3)符合 HAP 的病例定义。HAP 在重症监护病房(8.1%;95%CI:7.4-8.9)和调查当天插管的患者中最为常见(15%;95%CI:14-17;n=737 例有 HAP)。报告的最常见微生物是 (1,403 株分离株中 17%),其次是 (12%)和 spp.(12%)。分离微生物中普遍存在抗菌药物耐药性。最常开的抗菌药物组是青霉素类,包括与β-内酰胺酶抑制剂的组合。HAP 在插管和非插管患者中经常发生,不同医学专业之间存在显著差异。HAP 仍然是预防干预的重点,包括监测。我们的数据为不同环境下 HAP 的未来流行率提供了参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bd3/6092912/544345128267/1700843-f1.jpg

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