Murray H W
Annu Rev Med. 1986;37:61-9. doi: 10.1146/annurev.me.37.020186.000425.
Several factors appear to determine cellular resistance to protozoal infection. As judged by the interaction at the cellular level between the oxygen-dependent and -independent antimicrobial mechanisms of the human mononuclear phagocyte and the intracellular protozoa, Toxoplasma gondii and Leishmania donovani, these determinants include the cell's state of maturation and activation, the magnitude of the phagocyte's oxidative burst capacity, the ability of the cell to respond specifically to parasite ingestion with the production of toxic oxygen intermediates, parasite susceptibility to H2O2, and the presence of and protozoan susceptibility to oxygen-independent mechanisms.
有几个因素似乎决定了细胞对原生动物感染的抵抗力。从人类单核吞噬细胞与细胞内原生动物（刚地弓形虫和杜氏利什曼原虫）的需氧和非需氧抗菌机制在细胞水平上的相互作用来看，这些决定因素包括细胞的成熟和激活状态、吞噬细胞氧化爆发能力的大小、细胞对寄生虫摄取产生毒性氧中间体的特异性反应能力、寄生虫对过氧化氢的敏感性，以及非需氧机制的存在和原生动物对其的敏感性。
