Ngo Huy X, Garneau-Tsodikova Sylvie
University of Kentucky , 789 South Limestone Street , Lexington , KY 40536-0596 , USA . Email:
Medchemcomm. 2018 Apr 23;9(5):757-758. doi: 10.1039/c8md90019a. eCollection 2018 May 1.
Are small molecules or biologics the drugs of the future? Small-molecule drugs have historically been the pillars of traditional medicine. However, recently, we seem to be amidst a scientific revolution with the rise of many FDA-approved biologic drugs. This opinion article looks at the current state of small molecules and biologics and assesses what the future holds for these two broad classes of drugs.
小分子药物还是生物制剂将成为未来的药物?从历史上看,小分子药物一直是传统医学的支柱。然而,最近,随着许多获得美国食品药品监督管理局(FDA)批准的生物制剂药物的兴起,我们似乎正处于一场科学革命之中。这篇观点文章审视了小分子药物和生物制剂的现状,并评估了这两大类药物的未来走向。