Munawar Qureshi Awais, Mustansar Zartasha, Mustafa Samah
Research Center for Modeling and Simulation (RCMS), National University of Sciences and Technology (NUST), H-12 Islamabad 44000, Pakistan.
College of Engineering, Salahaddin University, Erbil 44002, Iraq.
R Soc Open Sci. 2018 Jul 11;5(7):180319. doi: 10.1098/rsos.180319. eCollection 2018 Jul.
In this paper, a detailed analysis of microwave (MW) scattering from a three-dimensional (3D) anthropomorphic human head model is presented. It is the first time that the finite-element method (FEM) has been deployed to study the MW scattering phenomenon of a 3D realistic head model for brain stroke detection. A major contribution of this paper is to add anatomically more realistic details to the human head model compared with the literature available to date. Using the MRI database, a 3D numerical head model was developed and segmented into 21 different types through a novel tissue-mapping scheme and a mixed-model approach. The heterogeneous and frequency-dispersive dielectric properties were assigned to brain tissues using the same mapping technique. To mimic the simulation set-up, an eight-elements antenna array around the head model was designed using dipole antennae. Two types of brain stroke (haemorrhagic and ischaemic) at various locations inside the head model were then analysed for possible detection and classification. The transmitted and backscattered signals were calculated by finding out the solution of the Helmholtz wave equation in the frequency domain using the FEM. FE mesh convergence analysis for electric field values and comparison between different types of iterative solver were also performed to obtain error-free results in minimal computational time. At the end, specific absorption rate analysis was conducted to examine the ionization effects of MW signals to a 3D human head model. Through computer simulations, it is foreseen that MW imaging may efficiently be exploited to locate and differentiate two types of brain stroke by detecting abnormal tissues' dielectric properties. A significant contrast between electric field values of the normal and stroke-affected brain tissues was observed at the stroke location. This is a step towards generating MW scattering information for the development of an efficient image reconstruction algorithm.
本文对三维(3D)人体头部模型的微波(MW)散射进行了详细分析。这是首次运用有限元方法(FEM)研究用于脑卒检测的三维逼真头部模型的微波散射现象。与现有文献相比,本文的一个主要贡献是在人体头部模型中添加了更多解剖学上逼真的细节。利用磁共振成像(MRI)数据库,通过一种新颖的组织映射方案和混合模型方法,开发了一个三维数值头部模型,并将其分割为21种不同类型。使用相同的映射技术将非均匀和频散介电特性赋予脑组织。为模拟仿真设置,使用偶极天线设计了围绕头部模型的八元天线阵列。然后分析了头部模型内部不同位置的两种脑卒(出血性和缺血性),以进行可能的检测和分类。通过在频域中使用有限元方法求解亥姆霍兹波动方程来计算发射和后向散射信号。还进行了电场值的有限元网格收敛分析以及不同类型迭代求解器之间的比较,以便在最短计算时间内获得无误差结果。最后,进行了比吸收率分析,以研究微波信号对三维人体头部模型的电离效应。通过计算机模拟,可以预见,通过检测异常组织的介电特性,微波成像可有效地用于定位和区分两种脑卒。在脑卒中位置观察到正常脑组织和受脑卒中影响脑组织的电场值之间存在显著差异对比。这是朝着生成用于开发高效图像重建算法的微波散射信息迈出的一步。