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孕期梅毒:巴西南部某地区孕产妇及围产期特征的关联

Syphilis in during pregnancy: association of maternal and perinatal characteristics in a region of southern Brazil.

作者信息

Padovani Camila, Oliveira Rosana Rosseto de, Pelloso Sandra Marisa

机构信息

MSc, RN, Hospital e Maternidade Santa Rita, Maringá, PR, Brazil.

Post-doctoral fellow, Universidade Estadual de Maringá, Maringá, PR, Brazil. Scholarship holder at Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Brazil.

出版信息

Rev Lat Am Enfermagem. 2018 Aug 9;26:e3019. doi: 10.1590/1518-8345.2305.3019.

Abstract

OBJECTIVE

To analyze the prevalence of syphilis in during pregnancy and its association with socioeconomic characteristics, reproductive history, prenatal and labor care, and newborn characteristics.

METHOD

A retrospective, cross-sectional study based on gestational and congenital syphilis reports. A (records) linkage was performed in the Brazilian databases: "Information System for Notifiable Diseases" (Sistema de Informação de Agravos de Notificação - SINAN); "Live Births Information System" (Sistema de Informação sobre Nascidos Vivos - SINASC); and "Mortality Information System" (Sistema de Informação sobre Mortalidade - SIM).

RESULTS

The prevalence of gestational syphilis was 0.57%. The following associations of syphilis in pregnancy were found: non-white skin color/ethnicity (PR=4.6, CI=3.62-5.76); low educational level (PR=15.4; CI=12.60-18.86); and absence of prenatal care (PR=7.4, CI=3.68-14.9). The perinatal outcomes associated with gestational syphilis were prematurity (PR=1.6 CI=1.17-2.21) and low birth weight (PR=1.6; CI=1.14-2.28). Two deaths from congenital syphilis, one death from another cause and five stillbirths were reported.

CONCLUSION

The results signify a long way until reaching the World Health Organization's goal of eradicating congenital syphilis.

摘要

目的

分析孕期梅毒的患病率及其与社会经济特征、生育史、产前和分娩护理以及新生儿特征之间的关联。

方法

一项基于妊娠和先天性梅毒报告的回顾性横断面研究。在巴西数据库中进行了(记录)关联:“法定传染病信息系统”(Sistema de Informação de Agravos de Notificação - SINAN);“活产信息系统”(Sistema de Informação sobre Nascidos Vivos - SINASC);以及“死亡信息系统”(Sistema de Informação sobre Mortalidade - SIM)。

结果

妊娠梅毒的患病率为0.57%。发现孕期梅毒与以下因素有关联:非白色肤色/种族(PR = 4.6,CI = 3.62 - 5.76);低教育水平(PR = 15.4;CI = 12.60 - 18.86);以及未接受产前护理(PR = 7.4,CI = 3.68 - 14.9)。与妊娠梅毒相关的围产期结局为早产(PR = 1.6,CI = 1.17 - 2.21)和低出生体重(PR = 1.6;CI = 1.14 - 2.28)。报告了2例先天性梅毒死亡、1例其他原因死亡和5例死产。

结论

结果表明,距离实现世界卫生组织根除先天性梅毒的目标还有很长的路要走。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d47/6091379/3111a14912d5/0104-1169-rlae-26-e3019-gf1.jpg

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