Serwin Agnieszka Beata, Unemo Magnus
1Medical University in Bialystok, Department of Dermatology and Venereology, Bialystok, Poland
WHO Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
Przegl Epidemiol. 2016;70(2):273-280.
Syphilis, similar to most other sexually transmitted infections, disproportionally affects females more than males, including the risk of adverse outcome of pregnancy and infection in foetus.
To describe and analyse all cases of syphilis among female patients (pregnant and non-pregnant) treated in Bialystok, Poland in 2000-2015.
Retrospective analysis of sociodemographic, epidemiological and clinical characteristics of pregnant and non-pregnant syphilis-positive females.
From 2000 to 2015, 47 females were treated for syphilis: 17 (36.2%) were pregnant and 30 (63.8%) non-pregnant. The majority of patients in both groups were residents of urban areas (64.7% and 73.3%, P=0.6), and were married or in a long-standing relationship (94.1% and 60.0%, P=0.01). At least five lifetime sexual contacts had 17.5% of pregnant and 3.3% of non-pregnant females (P=0.04). The steady partner was the most probable source of infection in both groups (76.6% and 66.6%, P=0.4). Early latent syphilis was the most frequent stage of the disease in the pregnant women (94.1%) and secondary syphilis in the non-pregnant females (43.3%). In 58.8% of the pregnant females the first serological test for syphilis was performed after 10th week of pregnancy and nearly half of them did not present to any follow-up visit after treatment. In about one third of patients sexual contacts were not examined.
Syphilis among females, especially pregnant ones, remains a problem in North-East Poland. Syphilis screening is frequently conducted too late in the pregnancy, increasing the risk of infection in the foetus. Pregnant females frequently do not attend follow-up visits. Contact notification should also be improved.
梅毒与大多数其他性传播感染一样，对女性的影响比对男性更大，包括妊娠不良结局和胎儿感染的风险。
描述和分析2000年至2015年在波兰比亚韦斯托克接受治疗的女性患者（孕妇和非孕妇）中的所有梅毒病例。
对梅毒检测呈阳性的孕妇和非孕妇的社会人口统计学、流行病学和临床特征进行回顾性分析。
2000年至2015年，47名女性接受了梅毒治疗：17名（36.2%）为孕妇，30名（63.8%）为非孕妇。两组中的大多数患者都是城市居民（分别为64.7%和73.3%，P = 0.6），并且已婚或处于长期关系中（分别为94.1%和60.0%，P = 0.01）。至少有过五次终身性接触的孕妇占17.5%，非孕妇占3.3%（P = 0.04）。固定性伴侣是两组中最可能的感染源（分别为76.6%和66.6%，P = 0.4）。早期潜伏梅毒是孕妇中最常见的疾病阶段（94.1%），二期梅毒是非孕妇中最常见的疾病阶段（43.3%）。在58.8%的孕妇中，首次梅毒血清学检测在妊娠第10周后进行，其中近一半患者在治疗后未进行任何随访。约三分之一的患者未对性接触者进行检查。
女性梅毒，尤其是孕妇梅毒，在波兰东北部仍然是一个问题。梅毒筛查在孕期往往进行得太晚，增加了胎儿感染的风险。孕妇经常不参加随访。接触者通知也应得到改善。
