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与妊娠梅毒治疗不足相关的因素:系统评价。

Factors associated with inadequate treatment of syphilis during pregnancy: an integrative review.

机构信息

Universidade de São Paulo. Ribeirão Preto, São Paulo, Brazil.

出版信息

Rev Bras Enferm. 2022 Sep 9;75(6):e20210965. doi: 10.1590/0034-7167-2021-0965. eCollection 2022.

DOI:10.1590/0034-7167-2021-0965
PMID:36102473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9728816/
Abstract

OBJECTIVES

to analyze the evidence available in literature on factors associated with inadequate treatment of syphilis in pregnant women.

METHODS

an integrative review, carried out in the LILACS, CINAHL, Web of Science, Scopus, PubMed and EMBASE databases, with controlled descriptors therapeutic and prenatal syphilis.

RESULTS

nine publications composed the interpretative analysis, in which low education, income and maternal age, temporary lack of medication and HIV infection were associated with inadequate treatment of syphilis during pregnancy, in addition to delay or absence of prenatal care and receiving the 1st dose of penicillin, lack of tests or treatment less than 30 days before childbirth, and partners' low compliance with treatment.

FINAL CONSIDERATIONS

among the main factors associated with inadequate treatment, clinical and sociodemographic aspects stand out, as well as failures in drug dispensing, prescription and monitoring of treatment of pregnant women and their partners by the health system.

摘要

目的

分析文献中与孕妇梅毒治疗不充分相关的因素。

方法

对 LILACS、CINAHL、Web of Science、Scopus、PubMed 和 EMBASE 数据库进行综合回顾,使用治疗和产前梅毒的控制描述符。

结果

9 篇出版物进行了解释性分析,其中低教育水平、收入和母亲年龄、临时缺乏药物和 HIV 感染与怀孕期间梅毒治疗不充分相关,此外还包括产前保健的延迟或缺失,以及在分娩前 30 天内未接受首剂青霉素治疗、检测或治疗不足,以及伴侣治疗依从性低。

最终考虑

在与治疗不充分相关的主要因素中,临床和社会人口学方面以及卫生系统在药物配给、孕妇及其伴侣的处方和治疗监测方面的失败尤为突出。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72f4/9728816/c332e06a5b91/0034-7167-reben-75-06-e20210965-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72f4/9728816/c332e06a5b91/0034-7167-reben-75-06-e20210965-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72f4/9728816/c332e06a5b91/0034-7167-reben-75-06-e20210965-gf01.jpg

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MMWR Morb Mortal Wkly Rep. 2019 Mar 15;68(10):247-250. doi: 10.15585/mmwr.mm6810a4.
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Global burden of maternal and congenital syphilis and associated adverse birth outcomes-Estimates for 2016 and progress since 2012.
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