Messing with the Sentinels-The Interaction of with Dendritic Cells.

() is a dangerous pathogen as well as a frequent colonizer, threatening human health worldwide. Protection against infection is challenging, as the bacteria have sophisticated strategies to escape the host immune response. To maintain equilibrium with , both innate and adaptive immune effector mechanisms are required. Dendritic cells (DCs) are critical players at the interface between the two arms of the immune system, indispensable for inducing specific T cell responses. In this review, we highlight the importance of DCs in mounting innate as well as adaptive immune responses against with emphasis on their role in -induced respiratory diseases. We also review what is known about mechanisms that has adopted to evade DCs or manipulate these cells to its advantage.