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麻醉机中氧化亚氮的更安全使用——一项技术模拟

Safer employment of nitrous oxide in anesthesia machines-a technical simulation.

作者信息

Mitterlechner Thomas, Paal Peter, Schroeder Daniel C, Wenzel Volker, Herff Holger

机构信息

Department of Anesthesiology, Privatklinik Hochrum, Sanatorium der Kreuzschwestern, Rum, Austria.

Department of Anesthesiology and Intensive Care Medicine, Hospitaller Brothers Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria.

出版信息

Med Gas Res. 2018 Jul 3;8(2):54-56. doi: 10.4103/2045-9912.235127. eCollection 2018 Apr-Jun.

DOI:10.4103/2045-9912.235127
PMID:30112166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6070839/
Abstract

Several incidents of anesthesia-attributed mortality in the past were caused by misconnection of gas pipelines resulting in ventilation with pure nitrous oxide. A simple safety feature may be to "mark" nitrous oxide with a lower pressure than oxygen and room air within the hospital's gas pipeline system. Then, any misconnection of gas pipelines could be detected by pressure differences with a manometer in the anesthesia machine. To check technical suitability, we tested maximum achievable nitrous oxide flows of an anesthesia machine at different pressures in the nitrous oxide supply line. Using decreased pressures for nitrous oxide compared to oxygen did not result in decreased nitrous oxide flows, as long as pressure in the nitrous oxide supply line was >1500 hPa. A concept of different pressures for nitrous oxide and oxygen could be used to technically differentiate between those two gases, and to avoid potentially fatal misconnections.

摘要

过去几起与麻醉相关的死亡事件是由气体管道误连接导致纯氧化亚氮通气引起的。一个简单的安全措施可能是在医院的气体管道系统内,将氧化亚氮的压力标记得低于氧气和室内空气。然后,通过麻醉机中的压力计检测压力差,就可以发现任何气体管道的误连接情况。为了检验技术适用性,我们在氧化亚氮供应管线的不同压力下测试了麻醉机可实现的最大氧化亚氮流量。只要氧化亚氮供应管线中的压力>1500 hPa,与氧气相比降低氧化亚氮的压力并不会导致氧化亚氮流量减少。氧化亚氮和氧气采用不同压力的概念可用于从技术上区分这两种气体,并避免潜在的致命误连接。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8888/6070839/f1bf9ee7268f/MGR-8-54-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8888/6070839/f1bf9ee7268f/MGR-8-54-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8888/6070839/f1bf9ee7268f/MGR-8-54-g001.jpg

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本文引用的文献

1
Nitrous Oxide and Serious Long-term Morbidity and Mortality in the Evaluation of Nitrous Oxide in the Gas Mixture for Anaesthesia (ENIGMA)-II Trial.氧化亚氮与麻醉气体混合物中氧化亚氮评估的严重长期发病率和死亡率(ENIGMA)-II 试验。
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氧化亚氮:我们是否仍在权衡之中?当前争议的定性回顾。
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