Soeroso Noni Novisari, Tarigan Setia Putra, Saragih Wina, Sari Novie Diana, Lubis Netty, Lubis Humairah
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Sumatera Utara, Universitas Sumatera Utara Hospital, Jl. Dr. Mansyur No. 66, Medan, 20154, Sumatera Utara, Indonesia.
Department of Ophthalmology, Faculty of Medicine Universitas Sumatera Utara, H. Adam Malik General Hospital, Jl. Bunga Lau No. 17, Medan, 20136, Sumatera Utara, Indonesia.
Respir Med Case Rep. 2018 Aug 7;25:116-118. doi: 10.1016/j.rmcr.2018.08.005. eCollection 2018.
Orbital metastasis of lung adenocarcinoma is very rare. The incidence is only found to be approximately 7%-12% of lung cancer cases. The lack of knowledge about orbital metastasis results in misdiagnosis between malignant or benign lesion. This was a case of a 39-year-old woman complaining about a protruding left eye and a blind pain in the left eye characterized by hyperemesis eyeball. A CT scan of the orbital showed a soft tissue tumor in the fronto-naso-superomedial area of the left orbital with suspicion of infiltration of the medial rectus muscle, left bulbus oculi, lamina papyracea, and left frontal sinus wall which causes proptosis and soft tissue tumor in the left temporal region with suspicion of infiltration in the left sphenoid wing with an impression of metastasis. A Fine Needle Aspiration Biopsy (FNAB) in the temporal and intra-orbital region showed metastatic adenocarcinoma. Moreover, findings of the chest x-ray and chest CT scan concluded that there was a tumor in the left lung, and a bronchoscopy found adenocarcinoma as the biopsy results.
肺腺癌眼眶转移非常罕见。其发生率仅约占肺癌病例的7%-12%。对眼眶转移缺乏认识导致在恶性或良性病变之间出现误诊。这是一例39岁女性病例，主诉左眼突出及左眼隐痛，表现为眼球突出。眼眶CT扫描显示左眼眶额鼻上内侧区域有一软组织肿瘤，怀疑内侧直肌、左眼球、纸样板和左额窦壁受浸润，导致眼球突出，左颞区有软组织肿瘤，怀疑左侧蝶骨翼受浸润，考虑为转移瘤。颞部和眶内区域的细针穿刺活检（FNAB）显示为转移性腺癌。此外，胸部X线和胸部CT扫描结果显示左肺有肿瘤，支气管镜检查发现腺癌，活检结果证实。
